Lung transplant moms: does Baby's DNA raise rejection risk?

NCT ID NCT05689905

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether shared genetic markers (HLA) between a child and a lung donor increase the risk of organ rejection in mothers who had a lung transplant. Researchers collected DNA from children born to 11 transplant women in France between 2012 and 2021. The goal is to better understand pregnancy-related immune risks and improve future recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help doctors give better advice to lung transplant women about pregnancy risks.

What could go wrong

This is a small, completed study (11 participants) that only looks back at past pregnancies. It cannot prove cause and effect, and findings may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HM

    Marseille, 13005, France

  • Bordeaux University Hospital

    Bordeaux, 33000, France

  • Civils Hospitals Lyon

    Lyon, 69002, France

  • Cochin Hospital (AP-HP)

    Paris, 75014, France

  • Foch Hospital

    Suresnes, 92150, France

  • Grenoble University Hospital

    Grenoble, 38700, France

  • Marie Lannelongue Hospital (GHSJ)

    Le Plessis-Robinson, 92350, France

  • Nantes University Hospital

    Nantes, Loire Atlantique, 44093, France

  • Strasbourg University Hospital

    Strasbourg, 67200, France