Nantes University Hospital

This study is testing whether people with well-controlled eczema can safely take their medication (dupilumab) less often. It will compare a reduced dosing schedule to the standard schedule in 256 teens and adults over one year. The goal is to see if spacing out injections can mai…

This study is testing if giving patients extra oxygen through a nasal tube before and after ankle surgery helps prevent complications like infections and poor wound healing. It involves 200 adults with ankle fractures who are at higher risk for healing problems. Half will receive…

This study is testing whether transferring gut bacteria from a healthy donor (a fecal transplant) can prevent painful pouch inflammation from coming back in people who had surgery for ulcerative colitis. It compares the real transplant to a sham (fake) procedure in 42 adults whos…

This study is testing two new drug combinations for adults under 66 with newly diagnosed multiple myeloma. The goal is to see if these combinations can eliminate or control the very small number of cancer cells that might remain after initial treatment. Patients are assigned to o…

This study is comparing two ways to fix a severe leak in the heart's mitral valve. It is testing a less invasive procedure using a small clip (MitraClip) against traditional open-heart surgery. The goal is to see if the clip procedure works as well as surgery for high-risk patien…

This study is testing whether a highly concentrated extract from blue-green algae (spirulina), called Phycocare®, can protect against nerve damage caused by a chemotherapy drug called oxaliplatin. The trial involves 110 adults with advanced stomach, intestinal, or pancreatic canc…

This study aims to discover the genetic causes of two rare, complex heart defects present at birth. Researchers will analyze DNA from about 600 children with these conditions and their parents to find new genetic links. The goal is to build knowledge that could lead to better, mo…