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Gene hunt aims to unlock secrets of rare heart conditions

NCT ID NCT05330338

Ongoing Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for new genes that may cause certain types of congenital heart disease, specifically transposition of the great arteries. Researchers will collect DNA from up to 300 children with these heart defects and their parents to find genetic changes. The goal is to better understand the causes of these conditions, which could lead to more personalized care in the future. No new treatments are being tested.

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Conditions

The condition(s) this trial relates to.

congenital heart disease congenitally corrected transposition of the great arteries transposition of the great arteries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART DEFECTS, CONGENITAL

Contacts and locations

Locations

  • CHU Angers

    Angers, Maine-et-Loire, 49000, France

  • CHU Bordeaux

    Bordeaux, Gironde, 33000, France

  • CHU Lyon

    Lyon, Rhône, 69000, France

  • CHU Marseille

    Marseille, Bouches-du-Rhône, 13000, France

  • CHU Nancy

    Nancy, Meurthe-et-Moselle, 54000, France

  • CHU Nantes

    Nantes, Loire-Atlantique, 44000, France

  • CHU Rennes

    Rennes, Brittany Region, 35000, France

  • CHU Rouen

    Rouen, Seine-Maritime, 76000, France

  • CHU Toulouse

    Toulouse, Haute-Garonne, 31000, France

  • CHU Tours

    Tours, Val de Loire, 37000, France

  • CHU de Caen

    Caen, Normandy, 14000, France

  • CHU de Lille

    Lille, Hauts-de-France, 59000, France

  • Groupe Hospitalier St Joseph - Hôpital Marie Lannelongue

    Le Plessis-Robinson, Hauts-de-Seine, 92350, France

  • Hôpital Européen Georges Pompidou

    Paris, Paris, 75000, France

  • Hôpital Nord Laennec

    Saint-Herblain, Loire-Atlantique, 44093, France

  • Intercard Lille

    Lille, Nord, 59000, France

More trials for these conditions

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