Heart drug study halted early: what we know

NCT ID NCT06005428

Terminated Disease control Sponsor: Cardurion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called CRD-4730 in people with a rare inherited heart rhythm disorder (CPVT) that can cause dangerous fast heartbeats. Seven adults received two different doses of the drug and a placebo to check safety and how the body processes it. The study was stopped early, so results are limited.

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Conditions

The condition(s) this trial relates to.

catecholaminergic polymorphic ventricular tachycardia catecholaminergic polymorphic ventricular tachycardia 1 congenital heart disease heart disorder ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CPVT1 HEART DEFECTS, CONGENITAL HEART DISEASES VENTRICULAR TACHYCARDIA

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
British Columbia Children&#39;s Hospital

Vancouver, British Columbia, V6H 3N1, Canada
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Cleveland Clinic Children&#39;s Hospital

Cleveland, Ohio, 44195, United States
Groupe Hospitalier Bichat Claude Bernard

Paris, 75018, France
Hôpital Louis Pradel

Bron, 69677, France
Hôptal Nord Laennec

Nantes, Loire-Atlantique, 44805, France
IRCCS Pavia Istituti Clinici Scientifici Maugeri Spa Società Benefit

Pavia, Lombardy, 27100, Italy
Stollery Children&#39;s Hospital University of Alberta

Edmonton, Alberta, T6G 2R7, Canada
University of British Columbia (UBC) Hospital

Vancouver, British Columbia, V5Z 1M9, Canada
University of Western Ontario

London, Ontario, N6A 5A5, Canada

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