Simple urine test may predict kidney recovery after acute failure

NCT ID NCT02889575

Completed Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 287 patients with acute kidney injury caused by tubular necrosis. Researchers measured two substances in urine (PIIINP and NGAL) to see if they could predict whether kidney function would return or if chronic kidney disease would develop. The goal is to find a simple test that helps doctors make better treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple urine test that helps doctors predict which patients will recover kidney function and which will develop long-term kidney failure.
What could go wrong: This is an observational study, not a treatment trial. The biomarkers may not prove accurate enough for routine use, and results may not apply to all kidney injury patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury acute kidney tubular necrosis chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY TUBULAR NECROSIS ACUTE RENAL FAILURE CHRONIC KIDNEY FAILURE

Contacts and locations

Locations

CHU de Nantes

Nantes, 44093, France

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