Can a simple breath test protect dialysis Patients' brains?
NCT ID NCT05445219
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how kidney dialysis affects brain blood flow in 37 adults with chronic kidney failure. Researchers use a special breathing device called RespirAct to measure the brain's response to carbon dioxide before and after dialysis sessions. The goal is to find ways to adjust dialysis to reduce stress on the brain and potentially prevent cognitive decline.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RespirAct device (diagnostic test measuring brain blood flow response to CO2)
What this could lead to
If successful, this could help doctors adjust dialysis to better protect the brain and reduce cognitive decline in kidney patients.
What could go wrong
This is a small, early-stage study with only 37 participants. It is designed to gather information, not to test a treatment, so it may not lead to immediate changes in care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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London Health Sciences Centre
London, Ontario, N6A 5W9, Canada