Which works best for high potassium? new study tests three emergency options

NCT ID NCT04012138

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared three emergency treatments for dangerously high potassium levels: insulin with dextrose, nebulized salbutamol, or a combination of both. Researchers measured how well each lowered potassium within 60 minutes. The trial involved 419 adults in emergency departments to find the safest and most effective approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Salbutamol and insulin aspart

What this could lead to

If successful, this trial could identify the most effective first-line treatment for acute hyperkalemia, improving emergency care and reducing complications.

What could go wrong

This is a completed Phase 4 trial, but results may not apply to all patient groups. The treatments have known side effects like low blood sugar or rapid heart rate.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperkalemia Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Agen Hospital

    Agen, France

  • Angers University Hospital

    Angers, France

  • Avicenne University Hospital

    Bobigny, France

  • La Pitié Salpêtrière University Hospital

    Paris, France

  • Lariboisiere Hospital

    Paris, France

  • Louis Mourier Hospital

    Colombes, France

  • Nancy University Hospital

    Nancy, France

  • Nantes University Hospital

    Nantes, France

  • Nice University Hospital

    Nice, France

  • Poitiers University Hospital

    Poitiers, France

  • Rennes University Hospital

    Rennes, France

  • Saint Antoine University Hospital

    Paris, France

  • Strasbourg University Hospital

    Strasbourg, France

  • Tours University Hospital

    Tours, France

  • University Hospital, Clermont-Ferrand

    Clermont-Ferrand, France

  • University Hospital, Grenoble

    Grenoble, France