Which works best for high potassium? new study tests three emergency options

NCT ID NCT04012138

Completed Disease control Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared three emergency treatments for dangerously high potassium levels: insulin with dextrose, nebulized salbutamol, or a combination of both. Researchers measured how well each lowered potassium within 60 minutes. The trial involved 419 adults in emergency departments to find the safest and most effective approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Salbutamol and insulin aspart
What this could lead to: If successful, this trial could identify the most effective first-line treatment for acute hyperkalemia, improving emergency care and reducing complications.
What could go wrong: This is a completed Phase 4 trial, but results may not apply to all patient groups. The treatments have known side effects like low blood sugar or rapid heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hyperkalemia Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERKALEMIA

Contacts and locations

Locations

Agen Hospital

Agen, France
Angers University Hospital

Angers, France
Avicenne University Hospital

Bobigny, France
La Pitié Salpêtrière University Hospital

Paris, France
Lariboisiere Hospital

Paris, France
Louis Mourier Hospital

Colombes, France
Nancy University Hospital

Nancy, France
Nantes University Hospital

Nantes, France
Nice University Hospital

Nice, France
Poitiers University Hospital

Poitiers, France
Rennes University Hospital

Rennes, France
Saint Antoine University Hospital

Paris, France
Strasbourg University Hospital

Strasbourg, France
Tours University Hospital

Tours, France
University Hospital, Clermont-Ferrand

Clermont-Ferrand, France
University Hospital, Grenoble

Grenoble, France

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