Can adding urea to dialysis prevent dangerous brain swelling?

This study tests whether adding urea to the dialysis fluid can prevent dialysis disequilibrium syndrome — a set of neurological symptoms like headache, confusion, and seizures — in people with kidney failure who need urgent dialysis for severe electrolyte problems. Researchers will enroll 20 adults with very high blood urea levels who also have dangerous potassium or acid imbalances. The goal is to see if this simple addition allows safe, aggressive dialysis without causing brain-related side effects.