Institute Of Hematology & Blood Diseases Hospital, China

This early-stage study is testing whether modified immune cells called CAR-T cells can help achieve a functional cure for HIV. The trial involves a small number of HIV-positive adults whose virus is already well-controlled with standard medications. Researchers will monitor safet…

This early-stage study is testing the safety and finding the right dose of a new experimental treatment called CD5CART for adults with advanced blood cancers that have returned or stopped responding to standard therapies. The treatment involves collecting a patient's own immune c…

This early-stage study is testing the safety and finding the right dose of a new type of CAR-T cell therapy for adults with advanced CD7-positive blood cancers, specifically acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL), that have come …

This study is testing a new antibody drug called Anti-CD38 for children aged 6 and up with immune thrombocytopenia (ITP), a condition that causes low platelet counts and bleeding risk. The trial is for kids who haven't gotten better or who relapsed after standard treatments. Rese…

This early-stage study is testing whether a personalized cell therapy, similar to those used for some blood cancers, can help people with severe autoimmune diseases that haven't responded to standard treatments. Doctors will collect a patient's own immune cells, modify them to ta…

This study is testing a new treatment plan for adults newly diagnosed with a specific, aggressive type of blood cancer called Philadelphia-positive acute lymphoblastic leukemia. The plan uses a combination of targeted pills, a short course of chemotherapy, and a one-time infusion…

This study is comparing two treatment approaches for adults with higher-risk myelodysplastic syndrome (MDS), a serious bone marrow disorder. Researchers want to know if going straight to a stem cell transplant from a donor works as well as first trying other treatments to control…

This study is testing whether a drug called daratumumab works better than rituximab for children with immune thrombocytopenia (ITP), a condition that causes low platelet counts and bleeding risk. The trial is for children aged 6-18 whose ITP didn't improve or came back after stan…

This study is testing whether combining two existing drugs, rituximab and daratumumab, can help adults with a hard-to-treat form of immune thrombocytopenia (ITP). ITP is a condition where the immune system mistakenly attacks platelets, causing a risk of easy bruising and bleeding…

This major Phase 3 trial is testing a new, potentially gentler treatment combination for children and teenagers newly diagnosed with a specific, harder-to-treat form of leukemia called Philadelphia chromosome-positive B-ALL. The study aims to see if using newer targeted drugs (ol…

This study is testing whether using a mobile app can help children with acute lymphoblastic leukemia (ALL) better manage their long-term outpatient treatment. It aims to see if the app helps keep their white blood cell counts within a safe target range by tracking daily medicatio…

This study is testing whether adding a second drug (anti-CD38) to a standard treatment (rituximab) works better for adults with immune thrombocytopenia (ITP) whose platelet counts stayed low after steroid therapy. Researchers will compare the safety and effectiveness of the two-d…

This study is testing an oral medication called golidocitnib for people with slow-growing T/NK-cell lymphomas that have come back or haven't responded to prior treatments. The goal is to see if this once-daily pill can effectively shrink tumors and control the disease. Researcher…

This study is testing whether a drug called Daratumumab works better than the standard drug Rituximab for adults with immune thrombocytopenia (ITP), a condition that causes low platelets and bleeding risk. It's for people whose ITP didn't get better or came back after initial ste…

This study is testing whether the drug thalidomide, taken as a pill, can control symptoms of a rare blood cancer called large granular lymphocytic leukemia (LGLL). Researchers want to see if using thalidomide alone works well, based on promising results when it was combined with …

This large study aims to find out which of two chemotherapy combinations works better for older adults (ages 55-75) with a serious blood cancer called acute myeloid leukemia (AML). Researchers will compare a newer drug combo (Venetoclax + Azacitidine) against a standard, more int…

This study is testing a comprehensive support program for children and teenagers with thalassemia, a serious blood disorder. The program aims to help kids grow better, go through puberty normally, and improve their overall health and quality of life. It involves monitoring, educa…

This early-stage study is testing a single infusion of 'universal' CAR T-cells in adults with severe autoimmune diseases like lupus and scleroderma that have not improved with standard treatments. The therapy aims to target and remove harmful immune cells to potentially control t…

This study is testing a new treatment plan for adults newly diagnosed with a fast-growing blood cancer called B-cell acute lymphoblastic leukemia (B-ALL). The goal is to see if using lower-dose chemotherapy together with newer immune-targeting drugs can effectively control the di…

This early-stage study is testing whether stem cells from donated umbilical cords can safely help patients recover their blood cell counts after receiving CAR-T therapy for certain blood cancers. It will enroll up to 24 adults with leukemia, lymphoma, or myeloma who still have ve…

This study is testing a new treatment approach for adults newly diagnosed with a type of acute lymphoblastic leukemia (ALL). It combines standard chemotherapy with an immunotherapy called CAR-T cells, given after the initial chemo to help keep the cancer in remission. The goal is…

This study is testing whether a pill called Chidamide can help prevent a dangerous blood cancer (AML) from coming back after a stem cell transplant. It will involve about 134 patients who are at high risk of the cancer returning. One group will take the pill for up to two years, …

This study is testing a blood clotting treatment called prothrombin complex concentrate (PCC) for people with hemophilia A who have developed 'inhibitors' that make standard treatments ineffective. The research aims to see how well PCC controls bleeding episodes and how safe it i…

This study is testing a new combination of three drugs (venetoclax, ivosidenib, and azacitidine) for adults with a specific genetic form of acute myeloid leukemia (AML) who are eligible for intensive chemotherapy. The main goals are to find the safest dose of this triple-drug reg…

This study is testing whether combining two antifungal drugs works better than current treatments for a severe fungal infection called mucormycosis in adults with blood cancers like leukemia. About 60 participants will receive the drug combination and be closely monitored to see …

This study is testing a new combination of three drugs—zanubrutinib, obinutuzumab, and lenalidomide—for people newly diagnosed with a rare blood cancer called SBLPN. The goal is to see if this three-drug approach is safe and effective at controlling the disease. Researchers will …

This study is testing whether adding a new type of antibody drug to standard radiation treatment can better control a rare bone cancer called solitary bone plasmacytoma. The goal is to prevent the cancer from progressing into a more serious disease called multiple myeloma. The tr…

This study is testing whether a dietary supplement called sulforaphane, found in foods like broccoli, is safe and can help patients recover their blood cell counts faster after a cord blood transplant. It will involve 36 adults with serious blood cancers like leukemia who receive…

This study is watching how well and how safely a medication called L-AmB works to treat serious fungal infections in children and teenagers with blood cancers. These patients are already taking other drugs to prevent such infections, but the infections have broken through. Resear…

This study is testing a combination of three drugs (gilteritinib, venetoclax, and azacitidine) for adults and teens newly diagnosed with a fast-growing blood cancer called AML, who have a specific genetic change (FLT3 mutation) and are healthy enough for strong treatment. The mai…

This early-stage study is testing if an existing drug called methylene blue can help control severe side effects that sometimes occur after powerful cancer immunotherapies like CAR-T. The side effects, called CRS and ICANS, involve dangerous immune system overreactions and neurol…

This study is testing whether adding two rounds of CAR-T cell therapy to standard chemotherapy and a stem cell transplant can better control a rare and aggressive blood cancer called plasma cell leukemia. The treatment involves initial chemotherapy, followed by CAR-T cells, more …

This study is testing a new antibody treatment called CM336 for people newly diagnosed with systemic light chain amyloidosis, a serious disease where abnormal proteins build up in organs. The trial will enroll 21 participants at a single hospital in China to see how well the trea…

This early-stage study is testing whether a medication called Zoledronic acid, usually used for bone health, can help adults with a rare inherited blood disorder called Congenital Dyserythropoietic Anemia (CDA). The main goal is to see if the treatment can safely increase patient…

This study is testing a personalized immune cell therapy called BCMA-CAR-T for young adults newly diagnosed with multiple myeloma, a blood cancer. Researchers want to see if combining this therapy with a stem cell transplant is safe and works better than the cell therapy alone. T…

This study is testing the safety and effectiveness of a new type of CAR-T cell therapy called supCD7 CART for adults with CD7-positive blood cancers that have returned or not responded to standard treatments. The trial will enroll up to 12 patients with either acute myeloid leuke…

This study is testing a two-part treatment for patients with very high-risk multiple myeloma, a blood cancer, that hasn't responded well to standard first-line therapy. Doctors will collect a patient's own stem cells and immune cells, give a stem cell transplant, and then infuse …

This early-phase study is testing a new type of cell therapy called QT-019C for people with severe autoimmune diseases that have not improved with standard treatments. The therapy uses donated, 'universal' immune cells engineered to target and remove harmful immune cells. The mai…

This is an early-stage study to test the safety and find the right dose of a new type of CAR-T cell therapy for people with multiple myeloma that has come back or stopped responding to other treatments. The therapy, called CAR19-BCMA, is designed to attack cancer cells in two way…

This study aims to better understand the side effects that can occur when patients with aplastic anemia receive ATG or ALG therapy. Researchers will closely monitor 200 patients receiving this treatment for the first time to track common reactions like serum sickness and issues w…

This study aims to learn more about a rare childhood bleeding disorder called immune thrombocytopenia (ITP). Researchers will follow 500 children in China diagnosed with ITP to observe their symptoms, treatments, and long-term health. The goal is to identify patterns that can hel…

This study aims to understand how different living arrangements affect senior health by observing 1,500 people aged 60 and older. Researchers will compare health outcomes between those living in large elderly care complexes and those receiving care at home. The goal is to identif…

This study aims to understand if simple tests of the body's automatic nervous system (like heart rate changes when standing) can help predict who might develop a serious complication called acute Graft-versus-Host Disease (GvHD) after a stem cell transplant. Researchers will obse…

This study aims to gather detailed information on many different blood diseases in China, including cancers like leukemia and lymphoma, and conditions like hemophilia. It will follow 2,300 patients to learn how common these diseases are, what treatments patients receive, how well…