New drug cocktail aims to beat deadly fungus in blood cancer patients

NCT ID NCT07185503

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a combination of two antifungal drugs—liposomal amphotericin B plus either posaconazole or isavuconazole—in 60 adults with blood cancers who also have a serious fungal infection called mucormycosis. The goal is to see if the combo can clear the infection better and with fewer side effects than standard treatments. Participants will be closely monitored for symptom improvement, side effects, and survival over several months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liposomal amphotericin B combined with posaconazole or isavuconazole

What this could lead to

If this works, it could offer a more effective and safer treatment option for a deadly fungal infection in people with blood cancers.

What could go wrong

This is a small, early-phase study with only 60 participants and no comparison group. The combination may still cause serious side effects or fail to improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm Zygomycosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

    RECRUITING

    Tianjin, China

    Contact Email: •••••@•••••

  • Second Hospital of Tianjin Medical University

    NOT_YET_RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shengjing Hospital of China Medical University

    NOT_YET_RECRUITING

    Shenyang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of China Medical University

    NOT_YET_RECRUITING

    Shenyang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Harbin Medical University

    NOT_YET_RECRUITING

    Harbin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin First Central Hospital

    NOT_YET_RECRUITING

    Tianjin, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Haihe Hospital

    NOT_YET_RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-••••

  • Tianjin Union Medical Center of Nankai University

    NOT_YET_RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••