New drug cocktail aims to control mantle cell lymphoma without chemo

NCT ID NCT07261163

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This study tests a three-drug combination (obinutuzumab, zanubrutinib, and lenalidomide) as a first treatment for people with mantle cell lymphoma who have never had therapy. About 37 adults aged 18-80 will receive the drugs, and those at higher risk may also get CAR-T cell therapy. The goal is to see how well this approach controls the disease and whether it can be a chemotherapy-free option.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institute of Hematology and Blood Diseases Hospital ,Chinese Academy of Medical Sciences

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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