New study aims to tame harsh side effects of aplastic anemia therapy
NCT ID NCT07461116
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study watches 200 people with aplastic anemia who are getting ATG/ALG treatment for the first time. Researchers will track side effects like serum sickness, organ damage, and infusion reactions to learn how common and severe they are. The goal is to create better guidelines for managing these reactions and improving patient care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Aplastic anemia patients treated with ATG/ALG
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meet the diagnostic criteria for aplastic anemia (Camitta criteria); * Receiving ATG/ALG immunosuppressive therapy for the first time; Exclusion Criteria: * Previously received hematopoietic stem cell transplantation; * Aplastic anemia patients receiving ATG/ALG as part of transplant conditioning regimen;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Regenerative Medicine Center and Red Blood Cell Disorders Center
RECRUITINGTianjin, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New hope for older adults with rare blood disorder: safer transplant regimen under study
- New combo therapy for rare blood disorder shows promise
- Double stem cell transplant could be Game-Changer for rare blood disorder
- New study: which first treatment works best for severe aplastic anemia?
- New transplant recipe may tame severe anemia