Engineered immune cells take on lupus and scleroderma in new trial

NCT ID NCT07315087

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study is testing a new type of cell therapy (called QT-019C) in 12 adults with severe autoimmune diseases like lupus and scleroderma that have not responded to standard treatments. The therapy uses specially engineered immune cells from a healthy donor to target and potentially reset the faulty immune system. The main goal is to check safety, but researchers will also look for signs that the treatment can control the disease.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy anti-neutrophil cytoplasmic antibody-associated vasculitis granulomatosis with polyangiitis idiopathic inflammatory myopathy systemic lupus erythematosus systemic sclerosis thrombocytopenia due to immune destruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital

    RECRUITING

    Tianjin, China, China