Old drug, new hope: thalidomide shows promise for rare leukemia

NCT ID NCT06530576

First seen Nov 18, 2025 · Last updated May 12, 2026 · Updated 20 times

Summary

This study tests thalidomide alone as a treatment for symptomatic large granular lymphocytic leukemia (LGLL), a rare blood cancer. About 48 adults will take thalidomide daily for up to 3 cycles; if it doesn't work well enough, methotrexate is added. The goal is to see if thalidomide can improve blood counts and reduce symptoms, with the main focus on overall response rate.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.