Blue dye may tame dangerous immune reactions
NCT ID NCT07169487
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 25 times
Summary
This early-stage study tests whether adding methylene blue to standard care can safely reduce cytokine release syndrome (CRS) and neurotoxicity (ICANS) in 18 adults who developed these side effects after CAR-T or bispecific antibody treatment. Participants receive methylene blue intravenously for 3–5 days, and researchers monitor side effects, immune cell levels, and cancer response. The goal is to find a safe dose and see if it helps control these serious immune reactions without harming the anti-cancer effect.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute of Hematology & Blood Diseases Hospital
RECRUITINGTianjin, Tianjin Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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