PERIODONTAL DISEASES

This study tested whether a special bone graft material made with zinc and a blood-clot concentrate could help repair bone damage caused by gum disease. Thirty adults with gum disease received the treatment, and researchers measured gum health and bone healing. The goal was to se…

This study tested a chewing gum with dietary nitrates (like those in leafy greens and beets) to see if it helps gum and heart health. Thirty adults with mild to moderate gum irritation or bleeding were randomly assigned to use either the nitrate gum or a placebo gum for three wee…

This study looked at whether adding a 980nm diode laser to standard deep-cleaning treatment for gum disease improves gum health and reduces body-wide inflammation. It included 40 people with gum disease who were either generally healthy or had a heart attack in the last 6 months.…

This study tested a special gum surgery technique (EPPT) alone or combined with enamel matrix derivative and a bone graft material to treat bone defects caused by gum disease. Fifty-eight adults with moderate to advanced gum disease participated. The goal was to see if the combin…

This study tested whether a probiotic called TCI188 (Pediococcus acidilactici) can improve oral health in adults with severe gum disease. 55 participants took the probiotic, and researchers measured changes in gum pocket depth and bleeding. The goal was to see if the probiotic co…

This study tested whether using a specially sized interdental brush (calibrated) is better than a regular one for reducing gum inflammation in young adults aged 18 to 30. Over three months, 51 participants used either a calibrated or non-calibrated brush daily. The goal was to se…

This study tested a less invasive gum surgery, alone or with added enamel matrix proteins and a bone graft, to treat bone defects caused by gum disease. 45 adults with deep gum pockets and bone loss participated. The goal was to see if adding these materials improves pocket depth…

This study looked at whether adding a special light therapy (antimicrobial photodynamic therapy) to standard deep cleaning helps treat gum disease. Twenty adults with deep gum pockets and bleeding were treated on both sides of the mouth—one side got the light therapy, the other d…

This study looked at whether smokers who switch to combustion-free nicotine products (like e-cigarettes or heated tobacco) see improvements in gum health and tooth appearance compared to those who keep smoking. Over 18 months, 460 healthy adults were followed. The goal was to mea…

This study tested whether adding a substance made from a patient's own blood (L-PRF) to standard gum surgery improves healing and reduces pain. Twenty-one adults with gum disease took part. The researchers compared standard surgery alone to surgery with L-PRF, measuring pocket de…

This study tested a gum surgery that combines a connective tissue graft with a special protein gel (enamel matrix derivative) to help regrow bone and gum tissue in people with advanced gum disease. Seventeen adults with deep gum pockets received the treatment, and researchers mea…

This study tested a new method to fix bone gaps that can happen when a dental implant is placed right after a tooth is pulled. Researchers used a plate made from the patient's own tooth to cover the gap, along with a tooth graft. The study included 63 adults aged 20 to 45 who nee…

This study tested whether adding antibiotics (amoxicillin and metronidazole) to standard deep-cleaning treatment helps adults with gum disease. Over 200 participants from dental practices across the U.S. took part. The goal was to see if the antibiotics improve gum pocket depth a…

This study tested whether a hyaluronic acid gel or a chlorhexidine mouthwash works better as a follow-up home treatment after deep cleaning for gum disease. Forty adults with periodontitis used one of the two products for 15 days after their dental cleaning. Researchers measured …

This study looked at whether three specific proteins in saliva can help tell the difference between healthy gums, gingivitis (mild gum inflammation), and periodontitis (serious gum disease). Researchers measured these proteins in 60 adults who were non-smokers and otherwise healt…

This study tested a new high-frequency ultrasound probe to see if it can measure gum pocket depth as accurately as the standard manual probing method for diagnosing periodontal disease. Thirty-nine adults participated, and researchers compared measurements from both methods. The …

This study tested whether lozenges made from propolis (a bee product) could reduce gum inflammation and plaque in 100 young adults aged 19–24 with moderate gingivitis. Participants used the lozenges for 7 days, and researchers measured gum health and saliva markers of inflammatio…

This study tested whether a special ultrasound tool that sprays hydroxyapatite (a natural enamel mineral) can make gum disease treatment more comfortable and reduce tooth sensitivity. Forty adults with advanced gum disease had half their mouth treated with the standard tool and t…

This study examined 318 adults to see if coffee drinking habits are linked to gum health. Participants were grouped by gum condition (healthy, gingivitis, or periodontitis) and asked about their coffee intake. Researchers measured plaque, bleeding, and gum pocket depth to find an…

This study looked at a protein called pentraxin in the gum fluid of teeth that support fixed dentures. The goal was to find early signs of gum disease that are not visible during a regular checkup. 90 adults who needed fixed dentures and had no visible gum inflammation took part.…

This study checked if multiple sclerosis (MS) is linked to gum disease. Researchers examined 293 Egyptian adults with MS. They measured gum health using a standard dental exam. The goal was to see how common gum disease is in people with MS.

This study looked at how diet might influence gum inflammation in healthy people. Researchers compared 36 vegans and omnivores to see if their gums reacted differently to plaque buildup. The goal was to understand if certain foods could affect gum health through changes in the bo…

This study looked at 61 adults with peripheral artery disease to see if gum health is linked to levels of TMAO, a chemical tied to heart risk. Researchers measured TMAO in blood and spit, comparing people with healthy gums, gum disease, or no teeth. The goal was to understand if …

This study looked at how gum disease (periodontitis) and Parkinson's disease might be connected through inflammation. Researchers compared saliva and blood samples from 60 people: those with both conditions, those with only gum disease, and healthy individuals. They found higher …

This study looked at whether adding einkorn, an ancient cereal, to the diet could change the types of bacteria in the mouth. Researchers focused on bacteria linked to gum disease and cancer risk. Thirty-one healthy adults ate einkorn and had their oral bacteria measured over time…

This study explored the connection between gum disease severity and levels of certain antibodies (ACPAs) in people with rheumatoid arthritis. Researchers measured these antibodies in gum fluid before and after non-surgical gum treatment. The goal was to better understand how gum …

This study looked at two proteins, Dkk-1 and sFRP5, in the gum fluid of 99 adults with healthy gums, gingivitis, or periodontitis. Researchers measured these proteins before and after non-surgical gum treatment to see if they could help track gum inflammation and bone loss. The g…

This study looked at levels of a hormone called prolactin in the gum fluid of 26 people with obesity and gum disease (stage II or III). Researchers measured prolactin before and after non-surgical gum treatment to see if it changed. The goal was to better understand the link betw…

This study looked at whether people with psoriasis have worse gum health and how that affects their quality of life. Researchers examined the mouths of 226 adults (some with psoriasis, some without) and asked them to fill out questionnaires. The goal was to better understand the …

This completed study looked at 108 Turkish adults to see if understanding dental health information is linked to gum health. Participants took a reading test about dentistry and had a dental exam. The goal was to find out if people with lower health literacy have worse gum diseas…

This study looked at a protein called IL-36α in the saliva and gum fluid of 80 people with healthy gums, gingivitis, or periodontitis. Researchers wanted to see if levels of this protein differ between these groups and relate to gum health. The goal was to better understand the b…

This study looked at whether certain substances in saliva can help tell the difference between healthy gums, gingivitis (early gum disease), and periodontitis (advanced gum disease). Researchers collected saliva from 60 non-smoking, healthy adults and measured levels of three mar…

This study looked at 100 people with gum disease, some with obesity and some without, to see how non-surgical gum cleaning affects their immune system. Researchers compared men and women to find differences in immune response and looked for tiny molecules called miRNAs that might…

This study looked at the bacteria in the mouths of 30 people—some with gastritis (stomach inflammation) and some without—to see if stomach health affects gum health. Researchers used advanced DNA testing to compare the types and amounts of bacteria. The goal was to understand the…

This study looked at how smoking impacts gum health in 484 adults. Half were current smokers, half were non-smokers. Researchers measured plaque, gum bleeding, pocket depth, and gum disease severity. The goal was to understand the link between smoking habits and periodontal disea…

This study looked at 400 dental and medical students to see if their dental and gum health affects how they feel about their quality of life. Researchers checked for plaque, gum inflammation, and cavities, and asked students to fill out a questionnaire about their oral health-rel…

This study explored whether poor oral health (like gum disease and cavities) contributes to ongoing inflammation and metabolic problems in people with HIV who are on antiretroviral therapy. Researchers observed 227 adults with HIV to measure dental health, bone density, and quali…

This study looked at 56 extracted human teeth to see how three different polishing methods—bristle brush, rubber cup, and air polishing—affect tooth surface roughness after scaling. The goal was to find which method makes teeth smoothest to help prevent plaque buildup. Results we…