PERIODONTAL DISEASES
Clinical trials for PERIODONTAL DISEASES explained in plain language.
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New gum surgery combo shows promise for repairing bone damage
Disease control CompletedThis study tested a special gum surgery technique (EPPT) alone or combined with enamel matrix derivative and a bone graft to repair bone defects between teeth caused by gum disease. 58 adults with moderate to advanced gum disease participated. The goal was to see if the combinati…
Matched conditions: PERIODONTAL DISEASES
Phase: PHASE4 • Sponsor: Rungta College of Dental Sciences and Research • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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Laser gum therapy may help heart attack survivors
Disease control CompletedThis study looked at whether using a 980nm diode laser along with standard deep cleaning can improve gum health and reduce body-wide inflammation in people with gum disease, including those who had a heart attack in the last 6 months. About 80 participants under 70 years old were…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Pomeranian Medical University Szczecin • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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Tooth-Based plate may improve dental implant success
Disease control CompletedThis study tested a new method to repair bone gaps around dental implants placed right after tooth removal. 63 adults with a non-restorable front tooth received either a standard membrane, a tooth graft, or a tooth graft plus a tooth plate. The goal was to see which approach gave…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Light therapy shows promise for treating gum disease
Disease control CompletedThis study tested whether adding a light-activated antimicrobial treatment to standard deep cleaning improves gum disease outcomes. Twenty adults with at least one deep gum pocket on each side of the mouth received standard cleaning on one side and cleaning plus the light treatme…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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New gum surgery aims to rebuild lost bone and tissue
Disease control CompletedThis study tested a specific gum surgery that combines a patient's own tissue graft with a protein gel to try to regrow bone and stabilize gum tissue lost to severe gum disease. Seventeen adults with advanced periodontitis received the surgery. Researchers measured changes in gum…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Phạm Đình Thiên Khải • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Zinc-Infused bone graft shows promise in repairing gum disease damage
Disease control CompletedThis study tested whether a special bone graft material (zinc-substituted nano-hydroxyapatite) combined with a concentrated blood clot block (advanced platelet-rich fibrin) could help repair bone damage caused by gum disease. Thirty adults with gum disease bone defects received t…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Suez Canal University • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Saliva test could reveal hidden gum disease clues
Knowledge-focused CompletedThis study looked at a protein called IL-36α in the saliva and gum fluid of 80 people—some with healthy gums, some with mild gum inflammation (gingivitis), and some with severe gum disease (periodontitis). The goal was to see if levels of this protein differ between these groups …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Ordu University • Aim: Knowledge-focused
Last updated May 01, 2026 19:27 UTC
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Ancient grain einkorn may fight mouth bacteria tied to cancer
Knowledge-focused CompletedThis study looked at whether eating einkorn, an ancient type of wheat, could change the bacteria in the mouth. Researchers wanted to see if this dietary change could reduce certain bacteria linked to a higher risk of cancer. Thirty-one healthy adults who ate a typical diet added …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 01, 2026 19:27 UTC
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Gum treatment study probes protein clues in gum disease
Knowledge-focused CompletedThis study looked at two proteins, Dkk-1 and sFRP5, in the fluid around gums to see if they change after non-surgical gum treatment. 99 adults with healthy gums, gingivitis, or periodontitis took part. Researchers measured these proteins before and after treatment to learn more a…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated May 01, 2026 19:27 UTC
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Gum disease and arthritis: surprising antibody link revealed
Knowledge-focused CompletedThis study looked at 36 adults with rheumatoid arthritis to see if the severity of gum disease is linked to levels of certain antibodies (ACPAs) found in gum fluid. Researchers measured these antibodies before and after non-surgical gum treatment. The goal was to better understan…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Misr International University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Smoking linked to worse gum disease in new study
Knowledge-focused CompletedThis study looked at 484 adults to see how smoking affects gum health. Researchers compared current smokers to non-smokers by measuring gum pockets, bleeding, and other signs of gum disease. The goal was to understand the link between smoking habits and periodontal health.
Matched conditions: PERIODONTAL DISEASES
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Psoriasis Patients' hidden oral health burden revealed
Knowledge-focused CompletedThis study examined the link between psoriasis (a chronic skin condition) and gum health in 226 adults. Participants with and without psoriasis had their gums checked and filled out questionnaires about how their mouth health affects their daily life. The goal was to understand i…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Scientists test three polishing tools to find the best way to keep teeth smooth and plaque-free
Knowledge-focused CompletedThis study looked at 56 extracted human teeth to compare three polishing methods—bristle brush, rubber cup, and air polishing—after scaling. The goal was to see which method makes the tooth surface smoothest, since a smoother surface can help prevent plaque buildup. Researchers u…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Khyber Medical University Peshawar • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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Gum health linked to dental knowledge in new turkish study
Knowledge-focused CompletedThis study looked at whether knowing more about dental health is linked to healthier gums. Researchers checked the dental knowledge and gum health of 108 Turkish adults. They found that people with lower dental health knowledge tended to have worse gum health. The results suggest…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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Saliva study seeks better way to spot gum disease
Knowledge-focused CompletedThis study looked at whether certain substances in saliva can help tell the difference between healthy gums, gingivitis (early gum disease), and periodontitis (advanced gum disease). Researchers measured three markers—Adseverin, 1-Alpha defensin, and sRANKL—in saliva from 60 non-…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Izmir Katip Celebi University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC