PERIODONTAL DISEASES

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will compare …

This study looks at how well 3D printed bone grafts work for supporting dental implants in people with gum disease or bone loss. Researchers will check if the implants stay stable and how much the graft shrinks over 1 to 6 years. About 100 healthy adults who already received this…

This study tests whether adding a special anti-inflammatory mouthwash to a deep-cleaning procedure helps heal advanced gum disease better than the cleaning alone. About 20 adults with severe gum disease will be randomly assigned to use either the active mouthwash or a placebo for…

This study compares three oral care routines in 90 adults aged 60+ who have gum disease and mild cognitive impairment. One group uses a special light device plus a manual toothbrush, another uses a powered toothbrush, and the control group uses a soft manual toothbrush. The goal …

This study aims to validate an Italian questionnaire for screening periodontitis (severe gum disease). Researchers will test how accurately the questionnaire identifies people with and without the condition, comparing it to a standard dental exam. About 495 adults across multiple…

This study is developing a new, non-invasive test for gum disease using a saliva sample and artificial intelligence. Researchers will collect saliva from 200 adults (some with gum disease, some healthy) and use a special sensor to detect disease-related signals. The goal is to cr…

This study tests whether breath samples collected in special bags remain accurate for diagnosing halitosis (bad breath) after 7 days. About 100 adults with gum disease will provide breath samples, which are analyzed immediately and again a week later. If the gas levels stay stabl…

This study aims to see if a self-reported questionnaire can accurately identify gum disease (periodontitis and gingivitis) compared to a standard dental exam. About 291 adults in Saudi Arabia will fill out the questionnaire and then receive a same-day clinical examination. The re…

This study will check if simple methods like taking mouth photos with a smartphone, answering a questionnaire, or getting a dental X-ray can accurately find gum disease. Researchers will compare these methods to a standard dental exam in 2,000 adults. The goal is to develop AI to…

This study follows 100 adults with healthy gums or various stages of gum disease over two years. Researchers collect saliva and plaque samples to see if certain biomarkers can predict who will develop or worsen gum disease. No treatments are given—the goal is simply to improve ea…

This study compares levels of oxidized LDL (a type of fat linked to heart disease) in the gum fluid of 40 adults aged 30-60 with severe gum disease versus healthy gums. Researchers aim to understand how gum inflammation might affect overall health, especially heart disease risk. …

This study will check for tiny plastic particles, called microplastics, in the deep gum pockets of 25 adults with severe gum disease (periodontitis). Researchers want to see if these particles are present and how much is there. The goal is to learn whether microplastics might mak…

This study looks at whether certain substances in saliva and fluid around dental implants can help detect and monitor peri-implantitis, a destructive gum disease around implants. Researchers will compare 80 adults with peri-implantitis, periodontitis, or healthy gums. The goal is…

This study will check levels of the Klotho gene and protein, along with certain bacteria and viruses in the mouth, in 108 adults with or without gum disease and acute coronary syndrome (a serious heart condition). The goal is to see if these factors are connected, which could hel…

This study looks at three methods dentists use to remove a tiny bit of enamel between teeth to make room for clear aligners. Seventy-five adults getting clear aligners will be randomly assigned to one of three techniques: manual strips, motor-driven strips, or abrasive discs. The…

This study looks at how certain proteins and antioxidants in the fluid around your gums change as your gums heal after a standard deep-cleaning treatment. Researchers will measure these substances in 21 adults with gum disease before treatment and again at 1 and 3 months after. T…

This study looks at the teeth, mouth, and face health of 25 people with Mowat-Wilson syndrome, a rare genetic condition. Researchers will check for cavities, gum disease, and facial features, and ask about quality of life. No treatment is given—the goal is to gather information t…

This study looks at whether teeth that bear more chewing force are more likely to have gum disease. Researchers will measure bite patterns in 50 adults using special software and check their gum health. The goal is to understand the connection between how we chew and periodontal …