PERIODONTAL DISEASES

This study tests whether a probiotic (Lactobacillus reuteri) is as good as a standard mouthwash (chlorhexidine) at reducing harmful bacteria in people with both gum disease and type 2 diabetes. Twenty participants will use one of the two treatments for 30 days. The goal is to see…

This study tests whether a graft made from a person's own extracted tooth, with or without low-level laser therapy, helps regrow jawbone after a tooth is pulled. About 21 healthy adults who need at least two back teeth removed and later replaced with implants will take part. The …

This study tests whether a protein from camel milk, made into tiny nanoparticles, can help repair bone damage caused by severe gum disease. About 44 adults with deep gum pockets and bone loss will receive the treatment during surgery. The goal is to see if the camel protein helps…

This study tests whether an AI-powered mobile app can help older adults in Hong Kong improve their gum health. 88 participants aged 60 and older will receive personalized oral hygiene instructions based on photos of their gums analyzed by the app. Trained volunteers will provide …

This study tests whether a patient's own stored tooth can be used as a graft to preserve jawbone after tooth extraction. About 21 adults needing at least two teeth pulled will receive this treatment. The goal is to maintain bone width and height for better future dental implant p…

This study looks at 50 people with gum disease—25 smokers and 25 non-smokers—to see how smoking affects a protein in saliva called histatin-1, which helps healing. Researchers measure gum health and protein levels before and up to three months after standard non-surgical gum trea…

This study watches 100 adults with liver cirrhosis to learn about their dental health and any barriers to getting dental care. Researchers will check for gum disease and see if regular dental cleanings help. The goal is to find ways to improve oral health in this group.

This study looks at how smoking changes the body's immune response in people with gum disease. Researchers compare smokers and non-smokers who have healthy gums, gingivitis, or periodontitis to measure specific proteins and genes linked to inflammation. The goal is to understand …

This study examines whether the Parkinson's drug Levodopa-Benserazide influences gum health and inflammation. Researchers will compare gum measurements and saliva samples from 136 people, including those with and without Parkinson's disease and with or without gum disease. The go…

This study follows 30 adults with periodontitis (a common gum disease) after they had gum surgery. Researchers want to see if surgery improves gum health and whether one type of surgery works better than another. Participants are checked regularly for pocket depth, bone levels, a…

This study looks at two different ways clear aligners are trimmed—one that sits on the gums and one that stops at the gum line—to see which leads to less plaque and healthier gums. Twenty adults with mild to moderate crowding will wear both designs at the same time (one on top, o…

This study looks at bacteria that enter the bloodstream during dental treatment for gum disease. Researchers want to find biological markers that can quickly tell if someone has a bloodstream infection, which could help diagnose sepsis faster. About 100 adults with gum disease ar…