NON-ALCOHOLIC FATTY LIVER DISEASE

This study tested whether taking specific probiotic supplements for 8 weeks could improve liver health in people with fatty liver disease (MASLD). 89 adults with the condition took either one of three probiotic strains or a placebo pill, while also taking a standard liver support…

This early-stage study tested the safety of a new weekly injectable drug, BI 3006337, in adults who have both overweight/obesity and fatty liver disease. The main goal was to find the highest dose participants could tolerate without serious side effects. Researchers also checked …

This study tested whether a specific probiotic bacteria, called L. lactis CKDB001, could improve liver health in people with non-alcoholic fatty liver disease (NAFLD). 95 adults with elevated liver enzymes took either the probiotic or a placebo daily for 12 weeks. Researchers mea…

This study tested if a medication called ornithine aspartate granules works as well as or better than a common supplement (silymarin) for treating non-alcoholic fatty liver disease (NAFLD). It involved 237 adults with NAFLD and measured if the treatment could reduce liver fat and…

This study tested whether drinking Jing-Si Herbal Tea could help people with non-alcoholic fatty liver disease (NAFLD). Over 100 adults with moderate NAFLD drank the tea or a placebo twice daily for 24 weeks. Researchers checked their blood tests, liver health, and weight to see …

This study tested whether motivational counseling could help people with non-alcoholic fatty liver disease (NAFLD) lose weight and improve their liver health. 231 adults with NAFLD were randomly assigned to receive either the counseling or standard care and followed for one year.…

This study tested whether a drug called tesamorelin could help people with obesity and nonalcoholic fatty liver disease (NAFLD). It involved 51 adults and aimed to see if the treatment could reduce harmful fat and inflammation in the liver. The drug works by boosting a natural ho…

This study tested whether a lifestyle program combining alternate-day fasting with exercise could be an effective, drug-free way to treat non-alcoholic fatty liver disease (NAFLD). It involved 80 adults with obesity and NAFLD, comparing changes in liver fat measured by MRI. The g…

This study looked at whether a common type of diabetes medication, called SGLT2 inhibitors, can improve liver health in people with type 2 diabetes. Researchers measured liver stiffness and fat using special ultrasounds and blood tests in 67 patients before and after 6 months of …

This study tested whether the drug efinopegdutide could help adults with nonalcoholic steatohepatitis (NASH), a serious form of fatty liver disease. Researchers compared the drug against a placebo in 381 participants over 52 weeks to see if it could clear liver inflammation witho…

This early-stage study tested a single dose of an experimental drug, GSK4532990, in 61 adults with non-alcoholic steatohepatitis (NASH), a type of fatty liver disease. The main goals were to see how the body processes the drug, how it affects the liver, and to check its safety. R…

This study tested a new ultrasound feature to see if it could measure liver fat in children as accurately as a standard MRI scan. It involved 30 children and teens at risk for or diagnosed with fatty liver disease. Each participant received both an investigational ultrasound and …

This study tested a new ultrasound feature to see if it could measure fat in the liver as well as a standard MRI scan. It involved 60 adults who were at risk for or had non-alcoholic fatty liver disease (NAFLD). Each participant had two special ultrasound exams and one MRI scan t…

This study tested if a new type of ultrasound scan could accurately measure how much fat is in a child's liver. Researchers compared the ultrasound results to standard MRI scans in about 90 children with or suspected of having fatty liver disease. The goal was to see if this simp…

This study aimed to find the best way to screen for advanced liver scarring (fibrosis) in people at high risk, such as those with type 2 diabetes or obesity. Researchers tested combinations of simple blood tests and a special ultrasound scan in 1,000 patients to see which method …

This study tested how consistent and reliable a special type of MRI scan, called LiverMultiScan, is for measuring liver health. Researchers scanned 61 volunteers with various liver conditions on different MRI machines to see if the results were the same each time. The goal is to …

This study looked back at the medical records of 263 adults with a confirmed liver disease called NASH to see if certain patient characteristics, other health conditions, or medications were linked to more severe liver scarring. Researchers analyzed data from 2013 to 2020 to iden…

This small, early-stage study aimed to understand how lowering insulin levels affects blood sugar in people at risk for fatty liver disease and type 2 diabetes. Eighteen participants with obesity and insulin resistance underwent two specialized medical procedures where their natu…

This study aimed to understand the financial and personal impact of non-alcoholic fatty liver disease (NAFLD) in Belgium. Researchers surveyed 73 adult patients with NAFLD to calculate their healthcare expenses and measure how the disease affected their quality of life. The goal …

This small, early-stage study aimed to understand if lowering high insulin levels could affect how the liver handles fat in people with fatty liver disease. For two weeks, 24 adults with overweight/obesity and insulin resistance took either a drug called diazoxide or a placebo. R…