NON-ALCOHOLIC FATTY LIVER DISEASE

This study looked at whether motivational interviewing, a type of counseling, helps people with non-alcoholic fatty liver disease (NAFLD) lose weight. 231 adults with NAFLD and a BMI of 25 or higher took part. Researchers measured weight, liver enzymes, and body fat changes after…

This study looked at whether alternating between fasting days and eating days, combined with exercise, could help people with non-alcoholic fatty liver disease (NAFLD) and obesity. Researchers measured changes in liver fat, weight, and blood markers in 80 participants. The goal w…

This study tested a drug called tesamorelin, which boosts growth hormone, in 51 obese adults with nonalcoholic fatty liver disease (NAFLD). The goal was to see if it could lower liver fat and improve liver inflammation and scarring. Participants received either tesamorelin or a p…

This study tested a new medicine called efinopegdutide in 381 adults with nonalcoholic steatohepatitis (NASH), a serious fatty liver disease that can lead to cirrhosis. The main goal was to see if the drug could reverse signs of liver inflammation without making scarring worse. R…

This study tested whether three types of probiotics could improve liver health in people with non-alcoholic fatty liver disease. 89 adults took probiotic capsules or a placebo daily for 8 weeks, along with a standard liver medication. Researchers measured changes in liver enzymes…

This study looked at whether changing the amount of methyl donor nutrients (like folate and choline) in the diet could help people with non-alcoholic fatty liver disease (NAFLD). 51 adults with low levels of these nutrients were enrolled. Researchers measured liver fat, body fat,…

This study tested whether giving people with non-alcoholic fatty liver disease (NAFLD) a device to monitor their liver fat at home could motivate them to lose more liver fat through diet and exercise. Ten adults with NAFLD used the device and received standard care. The goal was …

This study tested a single dose of the experimental drug GSK4532990 in 61 adults with NASH, a serious form of fatty liver disease. Researchers wanted to see how the drug moves through the body, how it affects liver proteins, and whether it is safe. The study is complete, and resu…

This study tested whether a probiotic called L. lactis CKDB001 can improve liver health in people with nonalcoholic fatty liver disease (NAFLD). About 95 adults with mildly elevated liver enzymes took the probiotic or a placebo for 12 weeks. The main goal was to see if the probio…

This study tested whether ornithine aspartic acid granules work better than silymarin capsules for people with non-alcoholic fatty liver disease (NAFLD). 237 adults with fatty liver and high liver enzymes took one of the two treatments for a period. The main goal was to see if li…

This study tested whether a special ultrasound technique can accurately measure liver fat in children with non-alcoholic fatty liver disease. About 90 kids aged 6-17, who were overweight or had type 2 diabetes, received both an ultrasound and an MRI. The goal was to see if the ul…

This study aimed to check how consistent and reliable a special type of MRI scan, called LiverMultiScan, is for measuring liver health. Researchers tested the scan on 61 adults with various liver conditions to see if it gave the same results when repeated on the same machine and …

This early-stage study tested a new medicine called BI 3006337 in 64 adults who are overweight or have obesity and also have fatty liver disease. Participants received weekly injections of either the study drug or a placebo for about 4 months. The main goal was to see what dose i…

This study looked at whether drinking Jing-Si Herbal Tea can improve health markers in people with non-alcoholic fatty liver disease (NAFLD). 108 adults with moderate NAFLD drank the tea for 24 weeks. Researchers measured changes in blood sugar, liver enzymes, cholesterol, and li…

This study looked at how different insulin levels impact blood sugar in 18 adults with overweight, insulin resistance, and non-alcoholic fatty liver disease (NAFLD). Participants underwent two procedures where insulin was either kept steady or slowly reduced, and researchers meas…

This study looked at 67 adults with type 2 diabetes and fatty liver disease who were starting a type of diabetes medication called SGLT2 inhibitors. Researchers measured liver stiffness and fat using ultrasound and checked blood markers before and 6 months after starting the drug…

This study looked at how consistent FibroScan, a non-invasive device that measures liver stiffness and fat, is when used by different people on different days. 108 adults with fatty liver or alcohol-related liver disease had multiple scans and blood tests over two visits. The goa…

This study looked at special proteins called immune semaphorins in people with fatty liver disease and NASH. The goal was to learn how these proteins might control inflammation in the liver and fat tissue. Researchers studied 148 obese patients to find new markers or future treat…

This study looked at whether fatty liver disease can help predict heart disease risk beyond traditional factors. Researchers measured blood markers of blood vessel damage in 63 adults aged 50-69 at high cardiovascular risk. The goal was to better understand the link between liver…

This study tested a new ultrasound feature that measures liver fat and compared it to the standard MRI method. 60 adults with or at risk for fatty liver disease had both scans. The goal was to see if the ultrasound could give similar results to the MRI, which could make liver fat…

This study looked at whether gut bacteria can get too close to the intestinal wall in people with non-alcoholic fatty liver disease (NAFLD). Researchers studied 38 adults aged 35-65 to measure this 'microbiome encroachment' and create a biobank for future research. The goal was t…

This study looked at the financial impact of non-alcoholic fatty liver disease (NAFLD) on 73 adults in Flanders, Belgium. Researchers measured healthcare costs and patient expenses using detailed questionnaires. The goal was to understand the economic burden of the disease, not t…

This study examined 263 patients with NASH (a type of fatty liver disease) to see how factors like age, other health problems, and medications relate to the severity of liver scarring. Researchers reviewed medical records from 2013 to 2020. The goal was to better understand which…

This study looked at whether a drug called diazoxide, which lowers high insulin levels, can change how the liver handles fat and sugar in people with overweight or obesity who have or are at risk for non-alcoholic fatty liver disease (NAFLD). Twenty-four adults took either a low …

This study tested a new ultrasound feature that measures liver fat in children and teens (ages 5-21) with or at risk for non-alcoholic fatty liver disease. Researchers compared the ultrasound results to standard MRI scans to see if the simpler, cheaper method works well. The goal…

This study looked at 1,000 adults aged 40-80 with type 2 diabetes or obesity to find the best way to screen for advanced liver scarring (fibrosis) caused by fatty liver disease. Researchers tested combinations of blood tests and a special ultrasound (FibroScan) to improve accurac…