Could a probiotic supplement help reverse fatty liver?
NCT ID NCT05804422
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests whether a daily probiotic lysate supplement can reduce fat and stiffness in the liver of adults with non-alcoholic fatty liver disease (NAFLD). Participants take either the supplement or a placebo for three months, and doctors measure changes using MRI and ultrasound. The goal is to see if this simple, over-the-counter-style approach can improve liver health without major side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probiotic lysate (postbiotic and metabiotic) from L. rhamnosus DV
What this could lead to
If effective, this supplement could offer a simple, safe way to reduce liver fat and improve liver health in people with NAFLD.
What could go wrong
This is a small, short-term study with only 39 participants. Results may not apply to everyone, and the supplement may not outperform placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Bogomolets National Medical University
Kyiv, 01601, Ukraine
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Center for Innovative Medical Technologies of the National Academy of Sciences of Ukraine
Kyiv, 02000, Ukraine
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Danylo Halytsky Lviv National Medical University
Lviv, 79010, Ukraine
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Kyiv City Clinical Endocrinology Center
Kyiv, 01601, Ukraine