New MRI scan could replace liver biopsies

NCT ID NCT03743272

Completed Diagnosis Sponsor: Perspectum Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested how well a special MRI scan called LiverMultiScan can measure liver fat, iron, and scarring. 61 adults with various liver diseases had up to 6 scans on different machines. The goal was to see if the results are consistent when repeated on the same scanner or on different types of scanners.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LiverMultiScan (a special MRI scan)
What this could lead to: If successful, this could help doctors use a non-invasive MRI scan to reliably measure liver health, reducing the need for biopsies.
What could go wrong: This is a small, early-stage study focused on technical accuracy, not on treating disease. It may not prove that the scan works in all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune hepatitis Cholangitis, Sclerosing cirrhosis of liver Fibrosis hereditary hemochromatosis liver disorder metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease primary biliary cholangitis primary sclerosing cholangitis viral hepatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE HEPATITIS CIRRHOSIS HEMOCHROMATOSIS LIVER DISEASES NON-ALCOHOLIC FATTY LIVER DISEASE NON-ALCOHOLIC STEATOHEPATITIS PRIMARY BILIARY CIRRHOSIS PRIMARY SCLEROSING CHOLANGITIS VIRAL HEPATITIS

Contacts and locations

Locations

Addenbrookes Hospital

Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
Leiden University Medical Centre

Leiden, Netherlands
Southampton General Hospital

Southampton, United Kingdom
University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR)

Oxford, Oxfordshire, OX3 9DU, United Kingdom

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