Fasting and exercise combo takes aim at fatty liver

NCT ID NCT04004403

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether alternate day fasting (eating only 600 calories on fast days) combined with regular aerobic exercise can reduce liver fat in people with non-alcoholic fatty liver disease (NAFLD). Eighty obese adults aged 18–65 with NAFLD participated. The goal was to see if this lifestyle approach could be an effective non-drug treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alternate day fasting and aerobic exercise

What this could lead to

If it works, this could offer a non-drug lifestyle approach to reduce liver fat and improve health in people with NAFLD.

What could go wrong

This is a small, completed trial with only 80 participants. Results may not apply to everyone, and sticking to the diet and exercise routine can be hard long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Illinois Chicago

    Chicago, Illinois, 60612, United States