Can lowering insulin help fatty liver? small study explores link

NCT ID NCT05729282

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 32 times

Summary

This study looked at whether a drug called diazoxide, which lowers high insulin levels, can change how the liver handles fat and sugar in people with overweight or obesity who have or are at risk for non-alcoholic fatty liver disease (NAFLD). Twenty-four adults took either a low or high dose of diazoxide or a placebo for two weeks. Researchers measured blood sugar, insulin, and fat levels to understand the role of high insulin in NAFLD.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.