New weekly shot aims to tackle fatty liver and obesity

NCT ID NCT05970640

Completed Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested an experimental drug called BI 3006337 in 64 adults who are overweight or obese and have fatty liver disease. Participants received weekly injections of either the drug or a placebo for about 4 months. The main goal was to check safety and tolerability, not yet to see if the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BI 3006337 (an experimental drug given as a weekly injection)
What this could lead to: If it works, this could point toward a treatment for fatty liver disease in people with overweight or obesity.
What could go wrong: This is a very early Phase 1 trial focused on safety, not effectiveness. The drug may cause side effects or fail to show benefit in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fatty liver disease metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-ALCOHOLIC FATTY LIVER DISEASE OBESITY

Contacts and locations

Locations

AMR Knoxville

Knoxville, Tennessee, 37920, United States
Accel Research Sites-Deland-67606

DeLand, Florida, 32720, United States
American Research Corporation at the Texas Liver Institute

San Antonio, Texas, 78215, United States
Catalina Research Institute, LLC-Montclair-49051

Montclair, California, 91763, United States
Centricity Research-Columbus-68879

Columbus, Ohio, 43213, United States
Endeavor Clinical Trials

San Antonio, Texas, 78240, United States
Floridian Clinical Research-Miami Lakes-68368

Miami Lakes, Florida, 33016, United States
The Liver Institute at Methodist Dallas

Dallas, Texas, 75203, United States
Velocity Clinical Research-Chula Vista

Chula Vista, California, 91911, United States
Velocity Clinical Research-La Mesa-69117

La Mesa, California, 91942, United States
Velocity Clinical Research-West Jordan-69043

West Jordan, Utah, 84088, United States
iResearch Atlanta

Decatur, Georgia, 30030, United States

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