LYMPHOMA

This study tested whether adding a drug called VIC-1911 to standard medications can prevent graft-versus-host disease (GVHD) and cancer relapse after a stem cell transplant. Sixteen adults with blood cancers like leukemia or lymphoma took part. The goal was to find the best dose …

This study tested a drug called brentuximab vedotin in 50 adults with a rare type of lymphoma that had come back or not responded to prior chemotherapy. The goal was to see how many patients had their tumors shrink or disappear. Results showed the drug can effectively control the…

This study looked at whether eating less fat and more fiber can lower the chance of a repeat Clostridioides difficile infection in people being treated for cancer. Eight patients with leukemia, lymphoma, or other cancers who had a recent C. diff infection took part. Researchers t…

This study tested the drug dasatinib in 17 people with chronic lymphocytic leukemia (CLL) who had already tried other treatments. The goal was to see if dasatinib could shrink or control the cancer. Researchers measured how many patients had a complete or partial response using s…

This early-stage trial tested a new drug called CUDC-907 in 26 children and young adults (ages 1-21) whose solid tumors, brain tumors, or lymphoma had stopped responding to standard treatments. The main goal was to find the safest dose and identify side effects. Researchers also …

This early-phase study tested an experimental drug (MK-1454) given as a shot into tumors, either alone or with the immunotherapy pembrolizumab, in 156 people with advanced solid tumors or lymphomas. The main goals were to find the safest dose and check for side effects. The study…

This study tested two different treatments for people newly diagnosed with a slow-growing type of lymphoma (follicular non-Hodgkin's lymphoma). Both treatments combined standard chemotherapy (CHOP) with a targeted antibody — either rituximab or a radioactive antibody called tosit…

This study tested a treatment for people with HIV who also have lymphoma (a type of blood cancer). It used very strong chemotherapy drugs followed by a stem cell transplant using the patient's own stem cells. The goal was to see if this approach is safe and possible for this grou…

This study tested an experimental tablet called XNW5004 in 120 adults with advanced tumors or lymphoma that had come back or stopped responding to standard treatments. The main goals were to check the drug's safety and find the best dose. Researchers also looked at how the drug m…

This early-phase study tested the safety of a drug called duvelisib when given with either romidepsin or bortezomib for people with T-cell lymphoma that returned or didn't respond to prior treatment. The study involved 114 adults and aimed to find the best dose with acceptable si…

This study tested a new cord blood product called NiCord, which is grown in a lab to have more stem cells, against standard cord blood transplants for people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord helps the body rebuild its blood and immune s…

This early-phase trial tested a new drug called LY3039478 in 247 people with advanced or metastatic cancer, including lymphoma. The main goal was to find a safe dose and see how the drug affects the body. Researchers also looked for signs that the drug might shrink tumors.

This study tested whether adding the drug bortezomib to a standard chemotherapy and antibody combination (BCVP-R) could improve outcomes for people with advanced follicular non-Hodgkin lymphoma who had not yet received treatment. A total of 95 participants were enrolled to see ho…

This study tested a new type of stem cell transplant for children and young adults (ages 2-21) with cancers that came back or didn't respond to treatment. The approach uses a special cell filter to speed up immune recovery after transplant. The main goal was to see if the procedu…

This study tested a combination of chemotherapy (CHOP), a targeted antibody (rituximab), and a radioactive antibody (Y90 ibritumomab tiuxetan) in 30 adults aged 65-80 with newly diagnosed large B-cell lymphoma. The goal was to see if this approach could improve event-free surviva…

This study tested a new drug, ALRN-6924, in 142 people with advanced solid tumors or lymphomas that have a normal p53 gene. The goal was to see if the drug is safe and can shrink tumors. Participants had cancers that did not respond to standard treatments. The study found the dru…

This study tested a drug called vorinostat in 56 people with follicular lymphoma or other slow-growing B-cell lymphomas that had returned or stopped responding to prior treatments. The main goal was to see if the drug could shrink tumors and to check its safety. The study was com…

This study tested a two-step stem cell transplant using a drug called cyclophosphamide to lower the risk of graft-versus-host disease (GVHD) in people with high-risk blood cancers like leukemia and lymphoma. 47 patients received a transplant from a matched sibling donor. The goal…

This study tested a new combination of three drugs (VIP152, venetoclax, and prednisone) in 8 adults with aggressive blood cancers like diffuse large B-cell lymphoma that had returned or not responded to prior treatments. The goal was to find a safe dose and see if the combination…

This study looked at whether a care plan led by a geriatrician and a nurse could help older adults (70+) with cancer live longer and feel better. It included 792 people with different cancers like breast, lung, or prostate. The approach was compared to usual cancer care to see if…

This study tested a web-based program to help children aged 8-17 with cancer (like leukemia or lymphoma) return to school. The program aimed to reduce social anxiety, improve coping skills, and boost school readiness. Twenty children and their parents took part, and the program w…

This study looked at whether covering the cost of blood transfusions would encourage people with blood cancers to enroll in hospice earlier. Many patients delay hospice because they need regular transfusions for symptom relief, which hospices often can't afford. The study offered…

This study tested a pain management program for 51 cancer survivors living in rural areas or who are Hispanic. The goal was to see if the program was easy to use and helpful for controlling cancer-related pain. Researchers measured how often participants used the program and how …

This study looked at medical records from over 2,700 people in Japan with a type of lymphoma (CD20-positive B-cell non-Hodgkin's lymphoma) who were treated with Rituximab Pfizer or Rituxan. The goal was to compare how often serious infections and low blood cell counts happened. T…

This study looked at whether a home-based exercise program is practical for people aged 65 and older with lymphoma, leukemia, or myeloma who are about to receive CAR-T cell therapy. Twenty participants were asked to do supervised resistance training and moderate aerobic exercise.…

This study watched 44 adults with leukemia or lymphoma who were getting CAR T-cell therapy. Researchers checked their heart health before and after treatment using heart scans and blood tests. The goal was to see how often heart problems happen and who might be at higher risk.

This study tested a new ultrasound method to see the smallest blood vessels in lymph nodes on the neck. Researchers scanned 20 adults (healthy and with head/neck cancer or lymphoma) to compare images from standard ultrasound and the new technique. The goal was to find out if this…

This study tested a new type of PET scan (called RGD-K5) to see how blood vessels in lymphoma tumors change after two rounds of chemotherapy. Twenty-one adults with large B-cell lymphoma and a tumor mass larger than 3 cm took part. The goal was to learn more about tumor blood ves…

This study looked at leftover tissue samples from 130 people with lymphoma or related conditions. Researchers measured proteins and chemical modifications on chromosomes to find patterns linked to different lymphoma types. No treatments were tested, but the findings may help scie…

This study tested a program designed to help adolescent and young adult cancer survivors (ages 15-39) find and use healthcare resources after treatment. The goal was to improve their health knowledge, self-care skills, and support, and to reduce cancer-related distress. 549 survi…

This study looked at whether cancer survivors living in rural areas can create their own survivorship care plans and learn via telehealth to improve their knowledge and confidence. 261 adults who finished treatment for breast, colorectal, lung, prostate cancer, or lymphoma took p…

This study looked at 126 adults aged 60 and older who had a bone marrow transplant for blood cancers like leukemia or lymphoma. Researchers measured physical and mental traits—like strength, memory, mood, and stress—to see which factors help people recover better. The goal was to…

This study looked at whether using telemedicine (remote doctor visits) can help people with aggressive lymphoma get their chemotherapy on time and at the right dose. Researchers compared patients who used telemedicine support to those who did not. The goal was to see if telemedic…

This study measured how anthracycline-based chemotherapy affects blood pressure control and artery stiffness in 60 people with breast cancer or lymphoma. Researchers compared patients currently on chemo with those who finished treatment 1-5 years ago. The goal was to understand w…

This study looked at 127 adults with diffuse large B-cell lymphoma who were treated with a common chemotherapy regimen called R-CHOP. The main goal was to see how often the treatment caused heart problems. Researchers tracked heart events and how well the cancer responded to ther…