New drug shows promise for Hard-to-Treat cancers with p53 gene

NCT ID NCT02264613

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new drug called ALRN-6924 in 142 people with advanced solid tumors or lymphomas that have a normal p53 gene. The goal was to see if the drug is safe and can shrink tumors. Participants had cancers that did not respond to standard treatments or had no standard options.

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Conditions

The condition(s) this trial relates to.

lymphoma mature T-cell and NK-cell non-Hodgkin lymphoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study site

    Birmingham, Alabama, 35294, United States

  • Study site

    Duarte, California, 91010, United States

  • Study site

    Denver, Colorado, 80218, United States

  • Study site

    Sarasota, Florida, 34232, United States

  • Study site

    Tampa, Florida, 33612, United States

  • Study site

    Boston, Massachusetts, 02114, United States

  • Study site

    Boston, Massachusetts, 02215, United States

  • Study site

    New York, New York, 10065, United States

  • Study site

    The Bronx, New York, 10461, United States

  • Study site

    Greenville, South Carolina, 29605, United States

  • Study site

    Nashville, Tennessee, 37203, United States

  • Study site

    Houston, Texas, 77030, United States

  • Study site

    Seattle, Washington, 98105, United States