New injection attacks tumors from inside out

NCT ID NCT04260529

Completed Disease control Sponsor: Cytovation AS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested an experimental drug called CyPep-1, injected directly into tumors, either alone or with the immunotherapy pembrolizumab. The study involved 60 adults with advanced solid cancers that had stopped responding to standard treatments. The main goals were to check safety and see if the drug could shrink injected tumors and even affect distant tumors.

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Conditions

The condition(s) this trial relates to.

cancer lymphoma metastatic melanoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMOR MALIGNANCY

Contacts and locations

Locations

EMC

Rotterdam, Netherlands
Institue Curie

Paris, France
Institute Gustave Roussy

Villejuif, France
LUMC

Leiden, Netherlands
NKI/AvL

Amsterdam, Netherlands
START

Madrid, Spain
UMCU

Utrecht, Netherlands
Vall d'Hebron (VHIO)

Barcelona, Spain

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