New injection targets tumors from inside out in advanced cancer trial

NCT ID NCT04260529

First seen Feb 01, 2026 · Last updated Apr 30, 2026 · Updated 8 times

Summary

This early-phase trial tested a new drug, CyPep-1, injected directly into tumors in 60 people with advanced solid cancers that had stopped responding to standard treatments. The study looked at safety and whether the drug, given alone or with the immunotherapy pembrolizumab, could shrink injected tumors and even distant ones. The goal was to find a safe dose and see early signs of tumor control, not a cure.

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Contacts and locations

Locations

  • EMC

    Rotterdam, Netherlands

  • Institue Curie

    Paris, France

  • Institute Gustave Roussy

    Villejuif, France

  • LUMC

    Leiden, Netherlands

  • NKI/AvL

    Amsterdam, Netherlands

  • START

    Madrid, Spain

  • UMCU

    Utrecht, Netherlands

  • Vall d'Hebron (VHIO)

    Barcelona, Spain

Conditions

Explore the condition pages connected to this study.