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Chemo heart risk under the microscope in lymphoma patients

NCT ID NCT02916316

Completed Knowledge-focused Sponsor: Fondazione Italiana Linfomi - ETS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 127 people with diffuse large B-cell lymphoma who were treated with a common chemotherapy regimen called R-CHOP. The main goal was to track how often heart problems occurred as a side effect of the treatment. Researchers also looked at how well the cancer responded and overall survival. The study did not test a new treatment but rather observed real-world outcomes to better understand heart risks.

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Conditions

The condition(s) this trial relates to.

Cardiotoxicity diffuse large B-cell lymphoma large B-cell lymphoma lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIFFUSE LARGE B-CELL LARGE B-CELL LYMPHOMA

Contacts and locations

Locations

  • A.O. Universitaria Ospedali Riuniti - Ospedale Umberto I Di Ancona

    Ancona, 60126, Italy

  • A.O. Universitaria Policlinico Di Modena

    Modena, MO, 41124, Italy

  • AO Riuniti Papardo Piemonte

    Messina, ME, 98158, Italy

  • AOU Universitа degli Studi della Campania Luigi Vanvitelli

    Naples, Italy

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, MI, 20162, Italy

  • Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova

    Reggio Emilia, 50139, Italy

  • Ematologia e Trapianto Istituto Regina Elena IFO

    Roma, Italy

  • Istituto Clinico Humanitas

    Rozzano, MI, Italy

  • Istituto Oncologico Veneto

    Padova, 35128, Italy

  • Nuovo Ospedale Di Sassuolo S.P.A.

    Sassuolo, Modena, 41049, Italy

  • Osp.Sant'Eugenio Divisione di Ematologia

    Roma, Italy

  • Ospedale Ca Foncello

    Treviso, Italy

  • Ospedale Riuniti di Foggia

    Foggia, Italy

  • Ospedale S. Giacomo di Castelfranco Veneto

    Castelfranco Veneto, Italy

  • Ospedali Riuniti Villa Sofia - Cervello

    Palermo, PA, 90146, Italy

  • U.O. Complessa di Ematologia Ospedale di Parma

    Parma, 43100, Italy

  • UO Ematologia PO Vito Fazzi

    Lecce, Italy

  • UO Ematologia e CTMO di Piacenza

    Piacenza, PC, 29121, Italy

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