New shot aims to stop Chemo's dangerous side effect
NCT ID NCT06521931
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested a new drug called PN20 in 24 adults with lymphoma or solid tumors who were getting chemotherapy. The goal was to see if a single injection before chemo could safely prevent a drop in platelets, which can cause bleeding. Researchers checked safety and whether platelet counts stayed high enough during treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PN20
What this could lead to
If successful, this could lead to a new option to prevent dangerously low platelet counts caused by chemotherapy, reducing bleeding risks and treatment delays.
What could go wrong
This is an early Phase 1 trial with only 24 participants, so safety and effectiveness are not yet proven. The drug may not work or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital of Hebei University
Baoding, Hebei, 071000, China
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Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, 646000, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450008, China
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The Affiliated Hospital of Qingdao University
Qingdao, Shandong, 266057, China
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The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, 471003, China
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Yiyang Central Hospital
Yiyang, Hunan, 413099, China