THROMBOCYTOPENIA

This program provides access to the medication eltrombopag for patients with medically significant thrombocytopenia (low platelet count). Eligible patients include those with chronic immune thrombocytopenia (ITP), severe aplastic anemia, or hepatitis C who need interferon therapy…

This study is testing a targeted radiation drug called 177Lu-PSMA-617 in men with advanced prostate cancer that has spread to the bone marrow and caused low blood cell counts. The main goal is to see if the treatment is safe and effective for this specific group of patients who o…

This study is testing whether giving a whole blood transfusion helps children survive severe malaria when they also have dangerously low platelet counts. Researchers in Zambia will randomly assign 132 children to either receive the transfusion or not, then track their recovery. T…

This study is testing if a drug called luspatercept can safely improve low blood cell counts in people with Clonal Cytopenia of Undetermined Significance (CCUS). CCUS is a condition where people have persistently low blood counts and genetic changes that put them at risk for deve…

This study aims to find the safest way to treat blood clots in cancer patients who also have low platelet counts, which increases their risk of dangerous bleeding. Fifty patients will be randomly assigned to receive either a full dose of blood thinners with platelet transfusions …

This study is testing whether the breast cancer drug T-DM1 can be safely given to patients who previously developed low platelet counts (thrombocytopenia) from chemotherapy. Researchers will enroll 56 breast cancer patients whose platelet counts have recovered after experiencing …

This study is testing if a drug called etamsylate can prevent serious bleeding in patients who have low platelet counts after a stem cell transplant. About 404 adult patients will be randomly assigned to receive either etamsylate or a placebo (inactive substance) to see which is …

This is an early-stage study to see if a new cell therapy called XJ-MK-002 is safe and can help raise platelet counts. The therapy involves a single injection of cells derived from umbilical cord blood. Researchers will test three different doses in a small group of adult cancer …

This study aims to find the best platelet transfusion level for extremely premature babies (born at 23-27 weeks). Researchers will compare whether using a lower platelet count as the trigger for transfusion is as safe as using a higher trigger. The goal is to improve survival wit…

This study is testing if an infusion of umbilical cord blood can safely help cancer patients whose platelet counts have dropped dangerously low due to their cancer treatments. The trial will enroll 25 patients aged 12-65 to receive the cord blood infusion and then track their pla…

This study is testing whether a specific lab test that looks for antibodies against a person's own platelets can help doctors diagnose immune thrombocytopenia (ITP) faster and more accurately. It will enroll 225 adults who have been found to have low platelet counts. The goal is …