THROMBOCYTOPENIA

This study tests a drug to help breast cancer patients whose platelet counts drop dangerously low after chemotherapy and T-DM1 treatment. It aims to see if the drug can safely raise platelet levels so patients can continue their cancer therapy. About 56 adults with breast cancer …

This study tests whether a lower dose of the blood thinner apixaban can safely treat blood clots in cancer patients who also have low platelet counts. About 30 participants will receive the adjusted dose, and researchers will track how many complete the treatment and how many hav…

This study tests the drug luspatercept in 50 adults with clonal cytopenias of uncertain significance (CCUS), a condition where blood cell counts are low and there is a risk of developing blood cancer. Participants receive injections every three weeks for up to 48 weeks. The goal …

This study tests whether etamsylate, a drug that helps blood clot, can prevent serious bleeding in people with very low platelet counts after a stem cell transplant. About 404 adults will receive either etamsylate or a placebo, and researchers will track who has a major bleed or …

This study looks at whether giving platelet transfusions only when platelet levels are very low is better for extremely premature babies (born at 23-26 weeks) than giving them at a higher threshold. The goal is to see if this approach helps more babies survive without major bleed…

This study tests if a single infusion of umbilical cord blood can safely raise platelet counts in 25 cancer patients aged 12 to 65 whose platelets dropped due to chemotherapy or other cancer treatments. Participants receive the infusion and are monitored for 28 days for platelet …

This study tests whether giving a whole blood transfusion to children under 5 with severe malaria and very low platelet counts can reduce the risk of death. About 132 children will be randomly assigned to receive either standard care plus a transfusion or standard care alone. The…

This program provides early access to ETB115 (eltrombopag) for people with thrombocytopenia (low blood platelets) who have no other treatment options and cannot join a clinical trial. It is for patients with serious or life-threatening conditions where the potential benefit outwe…

This early-stage study tests a single injection of umbilical cord blood cells (XJ-MK-002) in 16 adults aged 18-75 who have low platelets from cancer therapy. The main goal is to check safety and find the best dose. Researchers will monitor side effects and platelet counts for 28 …

This study looks at the best way to treat blood clots in cancer patients who also have low platelet counts, which raises bleeding risk. Researchers will compare two approaches: full-dose blood thinners with platelet transfusions, or a reduced dose without transfusions. The goal i…

This study is for adults with low platelet counts (thrombocytopenia) to see if a special blood test called MAIPA can help tell if the cause is autoimmune. Researchers will test for anti-platelet antibodies in 225 participants who have not yet started treatment. The goal is to imp…