New cocktail shows promise for Hard-to-Treat lymphoma

NCT ID NCT00428142

First seen Apr 01, 2026 · Last updated May 09, 2026 · Updated 5 times

Summary

This study tested whether adding the drug bortezomib to a standard chemotherapy and antibody combination (BCVP-R) could improve outcomes for people with advanced follicular non-Hodgkin lymphoma who had not yet received treatment. A total of 95 participants were enrolled to see how well the combination worked and what side effects occurred. The goal was to measure complete tumor disappearance and any severe nerve-related side effects.

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Contacts and locations

Locations

  • Allan Blair Cancer Centre

    Regina, Saskatchewan, S4T 7T1, Canada

  • BCCA - Fraser Valley Cancer Centre

    Surrey, British Columbia, V3V 1Z2, Canada

  • BCCA - Vancouver Cancer Centre

    Vancouver, British Columbia, V5Z 4E6, Canada

  • BCCA - Vancouver Island Cancer Centre

    Victoria, British Columbia, V8R 6V5, Canada

  • CHA-Hopital Du St-Sacrement

    Québec, Quebec, G1S 4L8, Canada

  • CHUM - Hopital Notre-Dame

    Montreal, Quebec, H2L 4M1, Canada

  • CancerCare Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Credit Valley Hospital

    Mississauga, Ontario, L5M 2N1, Canada

  • Cross Cancer Institute

    Edmonton, Alberta, T6G 1Z2, Canada

  • Hopital Charles LeMoyne

    Greenfield Park, Quebec, J4V 2H1, Canada

  • Humber River Regional Hospital

    Toronto, Ontario, M9N 1N8, Canada

  • London Regional Cancer Program

    London, Ontario, N6A 4L6, Canada

  • McGill University - Dept. Oncology

    Montreal, Quebec, H2W 1S6, Canada

  • Odette Cancer Centre

    Toronto, Ontario, M4N 3M5, Canada

  • QEII Health Sciences Center

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Regional Cancer Program of the Hopital Regional

    Greater Sudbury, Ontario, P3E 5J1, Canada

  • The Moncton Hospital

    Moncton, New Brunswick, E1C 6Z8, Canada

  • Thunder Bay Regional Health Science Centre

    Thunder Bay, Ontario, P7B 6V4, Canada

  • Univ. Health Network-Princess Margaret Hospital

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.