Ncic Clinical Trials Group

This phase II trial tested whether adding the drug bortezomib to a standard chemotherapy and antibody regimen (BCVP-R) could improve outcomes for 95 patients with advanced follicular lymphoma. The study measured how many patients had a complete response and how often severe nerve…

This study looked at whether taking letrozole, a hormone-blocking drug, could help prevent breast cancer from coming back in women who had already taken tamoxifen for at least 5 years. Over 5,000 women participated, and researchers measured how long they stayed cancer-free. The g…

This study tested whether giving higher doses of two chemotherapy drugs (epirubicin and docetaxel) along with a drug to boost immune recovery (pegfilgrastim) could help women with advanced or inflammatory breast cancer. 93 women took part. The goal was to see how well the treatme…