New hope for kids with resistant tumors? early trial tests CUDC-907
NCT ID NCT02909777
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study tested a new drug called CUDC-907 in 26 children and young adults (ages 1-21) with cancers that had come back or stopped responding to treatment, including solid tumors, brain tumors, and lymphoma. The main goal was to find a safe dose and check for side effects. Researchers also looked at how long the drug stayed in the body and whether it helped control the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CUDC-907
- What this could lead to
- If it works, this could point toward a new treatment option for children with hard-to-treat cancers that have not responded to standard therapies.
- What could go wrong
- This is an early Phase 1 trial with only 26 participants, focused on safety and dosing. It is too small to prove effectiveness, and the drug may cause side effects or not shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
-
Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
-
Texas Children's, Baylor College of Medicine
Houston, Texas, 77030, United States
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University of California, San Francisco, Benioff Children's Hospital
San Francisco, California, 94158, United States
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Other studies related to the condition(s) this trial covers.
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