CHRONIC LOW-BACK PAIN

This study tested if combining pain education with a medication called propranolol could help people with chronic low back pain or fibromyalgia. It was a small, early-stage trial to see if the approach was practical and acceptable to patients, and to get a first look at whether i…

This study tested whether acupuncture could help older adults (age 65+) manage chronic low back pain and improve their daily function. Researchers compared a standard 3-month acupuncture course and an extended 6-month course against usual medical care alone in over 800 participan…

This study tested whether teaching patients about the biology of pain, combined with rehabilitation, works better than traditional back education for reducing disability from chronic low back pain. Researchers compared these two educational approaches in 88 adults who had experie…

This study tested whether using a magnetic device to stimulate the brain, either alone or combined with specific back exercises, could reduce pain and improve function for people with long-term low back pain. It involved 140 adults who had experienced back pain for over three mon…

This study tested whether a biofeedback device could help people manage different types of chronic pain. 330 adults with chronic low back pain, recent breast surgery, or migraines were randomly assigned to either use the device with guidance or continue their usual care. The devi…

This study tested whether using virtual reality (VR) programs at home could help people manage chronic low back pain. Over 400 participants were randomly assigned to receive one of three types of VR therapy or a sham program, along with a Fitbit to track activity. Researchers mea…

This study tested whether adding dry cupping therapy to standard physiotherapy helps people with long-term, non-specific low back pain more than fake cupping plus physiotherapy. 48 participants were randomly assigned to receive either real or sham cupping for 10 sessions, along w…

This early-stage study tested an experimental injection called PP353 for people with long-term low back pain linked to specific spinal bone changes. The research involved 43 adults who hadn't gotten enough relief from standard treatments. The main goals were to check if the injec…

This early-stage study tested a new oral medication called PIPE-791 to see if it is safe and can help reduce pain. It involved 43 adults with long-term pain from knee arthritis or low back pain. Participants tried both the drug and a placebo for four weeks each to compare their e…

This study tested a procedure called pulsed radiofrequency (PRF) for people who still have significant back and leg pain after spinal surgery. About 130 participants received either the PRF treatment or standard steroid injections to see which better reduced pain and improved dai…

This study tested whether custom-made shoe inserts (orthotics) could help reduce chronic low back pain in people with flat, pronated feet. Researchers compared real custom orthotics to placebo inserts in 110 adults. The goal was to see if correcting foot alignment could ease back…

This study tested if adding special therapeutic tape or a specific massage technique to standard treatment helps people with long-term low back pain. Over three weeks, 102 participants received either standard care alone, standard care plus the tape, or standard care plus the mas…

This study tested whether combining antidepressant medication with specialized physical therapy works better than either treatment alone for people with chronic low back pain who also experience depression or anxiety. Researchers enrolled 308 adults who had back pain for over 6 m…

This study looked at whether a standard rehabilitation program helps people with long-term low back pain become more physically active and sit less. Researchers followed 89 patients to see if their activity levels and motivations changed during and after the program. The goal was…

This study tested a new virtual reality (VR) system designed to guide people through acupuncture imagery to help manage chronic low back pain. It involved 31 adults with long-term back pain to see if the VR treatment was safe, acceptable, and could reduce pain. The main goals wer…

This study tested if a new pain medication called HCP1004 works as well as an existing drug, RLD2401, for people with long-term low back pain. It involved 310 adults who had experienced pain for at least 3 months. The main goal was to see if the new drug provided similar pain rel…

This study tested if combining education about how pain works with light cycling exercise is better than just exercise alone for people with chronic low back pain. 24 adults were randomly assigned to either cycle while a therapist taught them about pain, or to just cycle. The goa…

This study tested whether a small implanted device that stimulates nerves (ReActiv8) works better than standard medical care for people with long-term low back pain. It involved 203 adults whose back pain hadn't improved with medications or physical therapy and who weren't candid…

This study tested whether a website called Rose, which provides therapeutic hypnosis recordings, could help adults manage chronic pain. One hundred participants with chronic pain used the app for 8 weeks while reporting on their pain levels, sleep, and mental health. The main goa…

This study tested whether a structured 4-week program that combined education, exercise, and mental health support worked better than standard care for people with chronic low back pain. 128 participants were randomly assigned to one of the two treatment groups. The main goal was…

This study tested a minimally invasive procedure called epiduroscopic adhesiolysis to relieve chronic back and leg pain. It compared results in 141 people who had prior unsuccessful back surgery to those who had never had spine surgery. The procedure uses a tiny camera to see and…

This pilot study tested whether weekly telehealth mindfulness sessions help people recover better from lumbar spine surgery compared to educational sessions. 67 adults recovering from their first back surgery were randomly assigned to receive 8 weeks of either mindfulness coachin…

This study tested if a combination of pain education and virtual reality (VR) exercise could help people with long-term low back pain. Forty adults with chronic pain received a one-hour educational session about how pain works in the brain and body, followed by 30 minutes of exer…

This study tested whether a 3-week digital sleep therapy program, delivered through a mobile app called SleepFix, could help reduce how much chronic low back pain interferes with daily life. Researchers compared the app to weekly sleep education emails in 106 adults who had both …

This small pilot study aimed to understand how fear of pain affects walking in people with chronic low back pain. Researchers measured walking patterns and pain levels in 16 participants while they walked normally and while distracted. The goal was to see if distraction could red…

This study aimed to understand how chronic low back pain affects movement stability. Researchers compared 70 participants—some with long-term back pain and some healthy volunteers—by measuring their movement patterns during different exercises. The goal was to gather knowledge ab…

This study aimed to understand why some people with chronic low back pain get better with certain treatments while others do not. Researchers tested four different 8-week treatments—mindfulness therapy, physical therapy, acupressure, and a medication—on nearly 500 participants. T…