Back pain breakthrough? study tests best anesthetic dose for epidural shots
NCT ID NCT00887003
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 252 adults with chronic low back pain to find the best volume and dose of local anesthetic when combined with a steroid in epidural injections. Participants received one of four dosing combinations over three injections in 12 months. Researchers measured pain relief, disability, anxiety, depression, and side effects to determine the optimal approach.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine (local anesthetic) and methylprednisolone (steroid)
What this could lead to
If successful, this could help doctors choose the best dose of anesthetic for longer-lasting pain relief with fewer side effects.
What could go wrong
This is a completed study comparing different doses, not testing a new drug. Results may not apply to all back pain patients, and some people may still get little relief or have side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC LOW-BACK PAIN are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Hamilton General Hospital
Hamilton, Ontario, Canada