Could a simple blood injection ease your back pain?

NCT ID NCT03712527

Completed Symptom relief Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single injection of platelet-rich plasma (PRP) into the spinal disc could reduce pain and improve function in people with chronic low back pain caused by active discopathy. 126 adults aged 18 to 60 with at least 3 months of pain received either PRP or a placebo (saline) injection. The main goal was to see if at least 30% more people in the PRP group reported meaningful improvement after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich plasma (PRP)
What this could lead to: If it works, this could offer a new, non-surgical option to ease pain and improve function for people with chronic low back pain from active discopathy.
What could go wrong: This is a small, early-stage trial with only 126 participants. The treatment may not work better than a placebo, and results may not apply to everyone with back pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW BACK PAIN

Contacts and locations

Locations

APHP Cochin

Paris, France
CHU Bordeaux

Bordeaux, France
CHU Nice

Nice, France
CHU Nîmes

Nîmes, France
CHU Toulouse

Toulouse, France
Univesity Hospital od Montpellier

Montpellier, 34295, France

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