Could a simple blood injection ease your back pain?

NCT ID NCT03712527

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single injection of platelet-rich plasma (PRP) into the spinal disc could reduce pain and improve function in people with chronic low back pain caused by active discopathy. 126 adults aged 18 to 60 with at least 3 months of pain received either PRP or a placebo (saline) injection. The main goal was to see if at least 30% more people in the PRP group reported meaningful improvement after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

platelet-rich plasma (PRP)

What this could lead to

If it works, this could offer a new, non-surgical option to ease pain and improve function for people with chronic low back pain from active discopathy.

What could go wrong

This is a small, early-stage trial with only 126 participants. The treatment may not work better than a placebo, and results may not apply to everyone with back pain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHP Cochin

    Paris, France

  • CHU Bordeaux

    Bordeaux, France

  • CHU Nice

    Nice, France

  • CHU Nîmes

    Nîmes, France

  • CHU Toulouse

    Toulouse, France

  • Univesity Hospital od Montpellier

    Montpellier, 34295, France