CHRONIC LOW-BACK PAIN

This study looks at two treatments for long-term low back pain caused by damaged spinal discs: a type of keyhole surgery (endoscopic discectomy) and a treatment using the patient's own stem cells. About 120 adults with confirmed disc pain will be followed to see which approach be…

This study explores whether specific colors of light presented to the eyes can lessen chronic pain in people with low back pain or fibromyalgia. Sixty adults will wear a light device for 2 hours daily over 5 days. The goal is to understand how light affects pain sensitivity and t…

This study tests whether two types of gentle brain stimulation—transcranial direct current stimulation (tDCS) and transcranial ultrasound (TUS)—can reduce pain and improve daily function in people with long-term low back pain. Researchers will compare active stimulation to a sham…

This study tests whether a smartphone app can help people with chronic low back pain feel better and move more easily. Up to 500,000 adults who have had back pain for at least 6 months will use the app to track symptoms, activity, and quality of life. The goal is to see if lifest…

This study tests if low-dose laser acupuncture can reduce pain and improve daily function in adults with chronic low back pain. About 80 people aged 18-65 with pain lasting 12 weeks or more will receive either real or fake laser treatment. The goal is to see if this gentle, non-i…

This study tests whether psilocybin therapy can help people better cope with chronic low back pain. About 30 adults aged 25-70 who have tried other treatments without success will receive a dose of psilocybin along with preparation and follow-up support sessions. The main goal is…

This study tests whether a single injection of platelet-rich plasma (PRP) into a damaged spinal disc can reduce pain and improve daily function in people with chronic low back pain. About 126 adults aged 18 to 60 with a specific type of disc inflammation (Modic 1) will receive ei…

This study compares two treatments for chronic low back pain caused by facet joints: standard radiofrequency ablation (RFA), which burns pain-signaling nerves, and a newer therapy called iovera°, which freezes those nerves temporarily without causing permanent damage. The goal is…

This study compares two treatments for chronic low back pain caused by disc disease: injections of a patient's own stem cells (from bone marrow) versus standard steroid injections. The goal is to see which provides better pain relief. The study was withdrawn before enrolling any …

This study aimed to check how well a spine implant called Arcadius XP L works and if it is safe for people with chronic low-back pain. The plan was to follow 60 patients for at least a year after surgery. However, the study was withdrawn before enrolling anyone, so no results are…