New pill aims to ease chronic pain without opioids

NCT ID NCT06810245

Completed Symptom relief Sponsor: Contineum Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested whether an experimental pill called PIPE-791 is safe and can lower pain in adults with long-term osteoarthritis knee pain or chronic low back pain. 43 participants stopped their usual pain meds, then took either the study drug or a placebo daily for 4 weeks, then switched for another 4 weeks. The main goal was to check for side effects and see if pain levels improved.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia Chronic Pain Low Back Pain neuralgia osteoarthritis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW-BACK PAIN CHRONIC OSTEOARTHRITIS PAIN

Contacts and locations

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Locations

Altoona Center of Clinical Research

Duncansville, Pennsylvania, 16635, United States
Arizona Research Center

Phoenix, Arizona, 85053, United States
Drug Studies America

Marietta, Georgia, 30060, United States
Drug Trials America

Hartsdale, New York, 10530, United States
JBR Clinical Research

Salt Lake City, Utah, 84107, United States