New implant offers hope for back pain sufferers

NCT ID NCT04803214

Completed Disease control Sponsor: Mainstay Medical Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested an implanted device called ReActiv8 against standard medical care for chronic low-back pain. 203 adults with long-lasting pain that didn't improve with other treatments took part. The device aims to stimulate back muscles to reduce pain and improve function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ReActiv8 implanted device

What this could lead to

If successful, this device could offer a new option for people with chronic low-back pain who haven't found relief from other treatments.

What could go wrong

This is a completed trial, but results may not apply to everyone. The device requires surgery, which carries risks like infection or device malfunction.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW-BACK PAIN

Contacts and locations

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Locations

Advent Health Shawnee Mission

Shawnee Mission, Kansas, 66204, United States
Ainsworth Institute of Pain Management

New York, New York, 10022, United States
Augusta Orthopedic & Sports Medicine Specialists

Augusta, Georgia, 30909, United States
Barrow Brain & Spine

Phoenix, Arizona, 85013, United States
Cantor Spine Center and Paley Orthopedic Spine Institute

West Palm Beach, Florida, 33407, United States
Center for Interventional Pain and Spine

Lancaster, Pennsylvania, 17601, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Cleveland Clinic Martin Health Tradition Hospital

Port Saint Lucie, Florida, 34986, United States
Columbia Orthopedic Group

Columbia, Missouri, 65201, United States
Duke University

Durham, North Carolina, 27710, United States
Freeman Hospital

Joplin, Missouri, 64804, United States
Horizon Clinical Research

Fayetteville, Georgia, 30214, United States
Indiana Spine Group

Carmel, Indiana, 46032, United States
International Spine, Pain and Performance Center

Washington D.C., District of Columbia, 20006, United States
Northwell Health

Great Neck, New York, 11021, United States
OrthoCarolina Sports Medicine Center

Charlotte, North Carolina, 28207, United States
OrthoIndy

Indianapolis, Indiana, 46278, United States
Pacific Research Institute

Santa Rosa, California, 95403, United States
Pacific Sports and Spine

Eugene, Oregon, 97401, United States
SSM Health Medical Group

Jefferson City, Missouri, 65109, United States
SoCal Sport and Spine

Newport Beach, California, 92660, United States
Spinal Diagnostics, PC

Tualatin, Oregon, 97062, United States
The Center for Clinical Research, LLC

Winston-Salem, North Carolina, 27103, United States
University Hospitals Cleveland

Cleveland, Ohio, 44106, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of Colorado

Aurora, Colorado, 80045, United States
University of Kansas Medical Center

Kansas City, Kansas, 66160, United States
Vista Clinical Research

Newnan, Georgia, 30265, United States