New drug shows promise for stubborn back pain
NCT ID NCT04238676
First seen Mar 29, 2026 · Last updated May 15, 2026 · Updated 5 times
Summary
This early-stage study tested an investigational drug called PP353 in 43 adults with chronic low back pain linked to a specific type of spine bone change (Modic 1). The main goals were to check safety and see if the drug reduces pain better than a placebo. Participants had to have moderate to severe pain and were followed for several months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CGM Research Trust
Christchurch, 8083, New Zealand
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Gildhøj Privathospital København
Copenhagen, 2605 Brøndby, Denmark
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Hospital Universitario LA PAZ
Madrid, Spain
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Hospital Vithas Granada
Granada, Spain
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Leeds General Infirmary
Leeds, LS1 3EX, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, Oxford, OX3 9DU, United Kingdom
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Royal Preston Hospital
Preston, Lancashire, PR2 9HT, United Kingdom
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University Hospital Coventry & Warwickshire
Coventry, CV2 2DX, United Kingdom
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University Hospital Of Wales
Cardiff, Wales, CF14 4XW, United Kingdom
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University Hospital Southampton Nhs Foundation Trust
Southampton, SO16 6YD, United Kingdom
Conditions
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