CHOLANGIOCARCINOMA

This study tested an immunotherapy drug called pembrolizumab in people with many different types of advanced solid tumors that had stopped responding to standard treatments. The main goal was to see if the drug could shrink tumors and to identify biological markers that might pre…

This large national trial is testing whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) can help control over 50 different types of rare cancers that have few or no standard treatment options. It enrolled over 800 adults whose rare cancers had progressed …

This study is testing a drug called entrectinib for people with advanced solid tumors that have specific genetic changes (NTRK, ROS1, or ALK gene rearrangements). It's a 'basket trial,' meaning it groups patients by their tumor's genetic type rather than where the cancer started …

This study aimed to test if a personalized immune cell therapy could prevent or delay the return of advanced gastrointestinal cancers (like pancreatic, liver, or colon cancer) after standard treatment like surgery. It was for patients whose cancer had specific genetic mutations a…

This early-stage trial is testing whether a specialized form of radiation therapy is safe for people with liver cancer who also have poor liver function or a reduced amount of healthy liver tissue. The study will enroll 36 patients to find the highest safe dose of radiation that …

This study is testing whether adding a drug called tucatinib to standard cancer treatments is safe and effective for people with HER2-positive cancers of the digestive system, like stomach, colon, and gallbladder cancers. It involves about 40 participants who have advanced cancer…

This study is testing whether a guided exercise program is safe, practical, and acceptable for older adults with liver cancer who are planning to have surgery. The main goal is to see if patients can and will participate in the program before their operation. Researchers will mea…

This early-stage study is testing a new imaging agent called 68Ga-FAPI-46 to see where it goes in the body of patients with many different types of cancer. The goal is to understand if this tracer can help doctors better see and understand tumors by highlighting specific cells ar…

This study is testing whether a new type of blood test can help doctors monitor patients with bile duct cancer (cholangiocarcinoma) after surgery. Researchers will check if specific markers in the blood can predict if the cancer is likely to come back or progress. The goal is to …