New pill aims to keep chemo on track for GI cancer patients
NCT ID NCT05772546
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether avatrombopag, a pill that boosts platelet production, can help people with gastrointestinal cancer who develop low platelets from chemotherapy. About 60 participants will receive either avatrombopag or a placebo. The goal is to see if the drug can raise platelet counts enough to prevent chemotherapy delays or dose reductions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Avatrombopag (Doptelet), a pill that boosts platelet production
- What this could lead to
- If it works, this could offer a new way to manage low platelets caused by chemotherapy, helping patients stay on schedule with their cancer treatment.
- What could go wrong
- This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02215, United States
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Oregon Health and Science University Hospital
Portland, Oregon, 97239, United States
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University of Miami Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of Washington Fred Hutchinson Cancer Center
Seattle, Washington, 98195, United States
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