New pill aims to keep chemo on track for GI cancer patients

NCT ID NCT05772546

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether avatrombopag, a pill that boosts platelet production, can help people with gastrointestinal cancer who develop low platelets from chemotherapy. About 60 participants will receive either avatrombopag or a placebo. The goal is to see if the drug can raise platelet counts enough to prevent chemotherapy delays or dose reductions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Avatrombopag (Doptelet), a pill that boosts platelet production

What this could lead to

If it works, this could offer a new way to manage low platelets caused by chemotherapy, helping patients stay on schedule with their cancer treatment.

What could go wrong

This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

camptodactyly-arthropathy-coxa vara-pericarditis syndrome chemotherapy-induced toxicity cholangiocarcinoma colorectal cancer digestive system cancer digestive system neoplasm esophageal cancer gallbladder carcinoma gastric cancer hepatocellular carcinoma malignant pancreatic neoplasm small intestine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02215, United States

  • Oregon Health and Science University Hospital

    Portland, Oregon, 97239, United States

  • University of Miami Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • University of Washington Fred Hutchinson Cancer Center

    Seattle, Washington, 98195, United States