New hope for Hard-to-Treat cancers: APL-5125 enters human trials
NCT ID NCT06399757
First seen Jan 11, 2026 · Last updated Jun 10, 2026 · Updated 18 times
Summary
This study tests a new drug, APL-5125, in adults with advanced solid tumors like colorectal, pancreatic, and ovarian cancer. The goal is to see if the drug is safe and can shrink or control tumors. About 100 participants will receive the drug in two phases to find the best dose and measure its effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Carolina BioOncology Institute
RECRUITINGHuntersville, North Carolina, 28078, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope
ACTIVE_NOT_RECRUITINGDuarte, California, 91010, United States
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City of Hope Orange County Lennar Foundation Cancer Center
ACTIVE_NOT_RECRUITINGIrvine, California, 92618, United States
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Duke Cancer Institute
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Florida Cancer Specialists & Research Institute
RECRUITINGSarasota, Florida, 34232, United States
Contact Email: •••••@•••••
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Mary Crowley Cancer Research
RECRUITINGDallas, Texas, 75251, United States
Contact Email: •••••@•••••
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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NEXT Oncology- San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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