CHOLANGIOCARCINOMA

This study tested a personalized treatment where a patient's own immune cells were modified in a lab to recognize and attack unique markers on their cancer cells. It involved 8 people with advanced solid tumors like lung, pancreatic, or ovarian cancer that had stopped responding …

This study tested a new drug called felmetatug vedotin, alone or with pembrolizumab, in people with advanced solid tumors (like ovarian, breast, lung, and others). The goal was to check safety and find the right dose. The trial was terminated early, so results are limited.

This early-phase study tested a new treatment called VAXINIA (a virus designed to attack cancer cells) in 66 adults with advanced solid tumors that had spread. The virus was given alone or with an immunotherapy drug (pembrolizumab), either as a shot into the tumor or through an I…

This early-stage study tested an experimental drug called INCB062079 in 25 people with advanced liver cancer (hepatocellular carcinoma) and several other solid tumors. The main goal was to check the drug's safety and find the highest dose people could tolerate. The study was term…

This study looked at genetic mutations in tumors from 565 people with advanced cancers of the digestive system, including liver, pancreas, and stomach. The goal was to see how often these mutations occur and whether they can help doctors choose more personalized treatments. The s…

This study looked at whether a simple blood test (called a liquid biopsy) could help doctors make better treatment decisions for people with advanced cancers of the colon, pancreas, or bile ducts. Researchers planned to enroll about 16 participants to see if the test results woul…

This study aimed to create a registry of tissue and blood samples from 1,000 people undergoing surgery or biopsy for liver or bile duct tumors. The samples were stored for future research to better understand these cancers and develop new treatments. The study was terminated earl…