Cancer gene hunt: could tumor maps guide better GI cancer treatment?

NCT ID NCT05489250

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at genetic mutations in tumors from 565 people with advanced gastrointestinal cancers, including liver, bile duct, gallbladder, pancreas, esophagus, and stomach cancers. The goal was to see how often these mutations could be targeted by existing drugs and to track whether using genetic information changed treatment decisions. The study was terminated early, so the full impact is unclear.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors choose more targeted treatments for gastrointestinal cancers based on a patient's tumor genetics.

What could go wrong

The study was terminated early, so results may be limited. It was observational, not testing a new treatment directly, so benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma esophageal cancer Esophageal Neoplasms extrahepatic bile duct carcinoma gallbladder cancer gallbladder carcinoma gallbladder neoplasm gastric cancer gastric neoplasm gastroesophageal junction adenocarcinoma hepatocellular carcinoma intrahepatic cholangiocarcinoma Liver Neoplasms malignant pancreatic neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm pediatric hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Augusta-Kranken-Anstalt Bochum

    Bochum, Germany

  • Bochum Uni

    Bochum, Germany

  • CaritasKlinikum Saarbrücken

    Saarbrücken, Germany

  • Ev. Kliniken Essen-Mitte, Klinik für Internistische Onkologie

    Essen, 45136, Germany

  • Evangelisches Waldkrankenhaus Spandau

    Berlin, Germany

  • Friedrich-Ebert-Krankenhaus Neumünster

    Neumünster, Schleswig-Holstein, 24534, Germany

  • GEFOS - Gesellschaft für onkologische Studien Dortmund

    Dortmund, Germany

  • HELIOS Klinikum Bad Saarow

    Bad Saarow, Germany

  • Hamburg Onkologische Schwerpunktpraxis Eppendorf

    Hamburg, Germany

  • KHNW Frankfurt

    Frankfurt am Main, Hesse, 60488, Germany

  • Klinik München-Bogenhausen

    München, Germany

  • Klinikum Chemnitz

    Chemnitz, Germany

  • Klinikum Lippe

    Lemgo, Germany

  • Klinikum Ludwigsburg

    Ludwigsburg, Germany

  • Klinikum Rheine, Mathias-Spital Rheine

    Rheine, Germany

  • Klinikum Wolfsburg

    Wolfsburg, Germany

  • Krankenhaus Barmherzige Brüder

    Regensburg, Germany

  • Langen, Gemeinschaftspraxis für Hämatologie und Onkologie

    Langen, Germany

  • MVZ Onkologische Kooperation Harz

    Goslar, Germany

  • MVZ Oskar-Helene-Heim Berlin

    Berlin, Germany

  • Marien Hospital Witten

    Witten, Germany

  • Medius Klinik Osterfildern-Ruit

    Ostfildern, Germany

  • Münster, Gemeinschaftspraxis für Hämatologie und Onkologie

    Münster, Germany

  • Onkologie Bodensee

    Singen, Germany

  • Onkologisches Zentrum Wolfsburg-Helmstedt MVZ GmbH

    Wolfsburg, Germany

  • Onkozentrum Dresden

    Dresden, Germany

  • Ortenau Klinikum Lahr-Ettenheim

    Lahr, Germany

  • St. Anna Hospital Herne

    Herne, Germany

  • Studienzentrum UnterEms

    Leer, Germany

  • Universitätsklinikum Halle (Saale)

    Halle, Germany

  • ÜBAG - MVZ Dr. Vehling-Kaiser GmbH

    Landshut, Germany