OESOPHAGEAL CANCER

This early-phase study tests a new drug called IPH5301 in people with advanced solid tumors that have spread. The drug works by blocking a protein (CD73) that tumors use to hide from the immune system. The study first finds the safest dose of IPH5301 alone, then tests it combined…

This study tests whether adding an immunotherapy drug (PD-1 inhibitor) to standard chemotherapy and radiation before surgery helps people with a certain type of esophageal cancer live longer. About 422 adults with stage T1-4aN1-3M0 or T3-4aN0M0 squamous cell esophageal cancer who…

This study looks at whether the things people buy at stores—like painkillers or indigestion remedies—could be early warning signs of cancer. Many cancers cause vague symptoms that people treat with over-the-counter products before seeing a doctor. Researchers will compare the sho…

This study observes 160 adults with newly diagnosed oesophageal cancer who are scheduled for endoscopic ultrasound (EUS) as part of their standard care. Researchers want to see how often EUS results lead to a change in treatment plan after initial CT and PET scans. They will also…

This study is for people with stomach, pancreas, or bowel cancer who are having surgery, as well as some people without cancer for comparison. The goal is to understand why some patients lose muscle and weight (cachexia) and how it affects their recovery. Researchers will track c…