New cancer drug trial halted early – what we know

NCT ID NCT05194072

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug, felmetatug vedotin, alone or with pembrolizumab, in people with advanced solid tumors like ovarian, breast, and lung cancer. The goal was to check safety and find the right dose. The trial was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenoid cystic carcinoma cholangiocarcinoma endometrial carcinoma endometrium neoplasm fallopian tube cancer fallopian tube neoplasm gallbladder carcinoma gallbladder neoplasm Her2-receptor negative breast cancer hormone receptor-positive breast cancer non-small cell lung carcinoma ovarian cancer ovarian neoplasm ovarian serous adenocarcinoma peritoneal neoplasm primary peritoneal carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AdventHealth Celebration Infusion Center

    Celebration, Florida, 34747, United States

  • AdventHealth Medical Group Oncology Research at Celebration

    Celebration, Florida, 34747, United States

  • Community Health Network, Inc.

    Indianapolis, Indiana, 46227, United States

  • Community Health Network, Inc.

    Indianapolis, Indiana, 46250, United States

  • Community Health Network, Inc.

    Indianapolis, Indiana, 46256, United States

  • Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • Hamato-Onkologische Phase 1 Unit der Charite/Charite Research Organisation

    Berlin, 12200, Germany

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Northwestern Medical Group

    Chicago, Illinois, 60611, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • Presbyterian/St Lukes Medical Center

    Denver, Colorado, 80218, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • START Madrid-Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    West Valley City, Utah, 84119, United States

  • Sarah Cannon Research Institute

    London, W1G 6AD, United Kingdom

  • Sarah Cannon Research Institute - Pharmacy

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • South Texas Accelerated Research Therapeutics, LLC

    San Antonio, Texas, 78229, United States

  • The Ottawa Hospital Cancer Centre

    Ottawa, Ontario, K1H 8L6, Canada

  • The University of Texas M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • The University of Texas MD Anderson Cancer Center Investigational Pharmacy Services

    Houston, Texas, 77030, United States

  • UCHealth Sue Anschutz-Rodgers Eye Center

    Aurora, Colorado, 80045, United States

  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP)

    Aurora, Colorado, 80045, United States

  • University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP)

    Aurora, Colorado, 80045, United States

  • University of Colorado Hospital - Anschutz Outpatient Pavilion (AOP)

    Aurora, Colorado, 80045, United States