New hope for advanced cancer patients? early trial begins

NCT ID NCT05627063

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new oral drug, ABSK121-NX, in people with advanced solid tumors that no longer respond to standard treatments. The main goal is to check safety and find the right dose. About 169 adults will take part, and researchers will also look for any signs that the drug shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma intrahepatic cholangiocarcinoma neoplasm urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, China

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, 89119, United States

  • Fujian Cancer Hospital (Department of Hepatobiliary and Pancreatic Oncology /Phase I Ward)

    Fuzhou, China

  • Gabrail Cancer Center Research

    Canton, Ohio, 44718, United States

  • Harbin Medical University Cancer Hospital (Gastroenterology Department 2nd Ward)

    Haerbin, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, China

  • Hunan Central Hospital

    Changsha, Hunan, China

  • Jilin Cancer Hospital

    Changchun, Jilin, China

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Liaoning Cancer Hospital (Phase I Ward)

    Shenyang, China

  • Mianyang Central Hospital

    Mianyang, Sichuan, China

  • Shanghai East Hospital Tongji University

    Shanghai, Shanghai Municipality, China

  • Shanxi Provincial Cancer Hospital

    Taiyuan, Shanxi, China

  • The Affiliated Hospital of Inner Mongolia Medical University

    Hohhot, Inner Mongolia, China

  • The First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

  • The First Hospital of China Medical University

    Shenyang, Liaoning, China

  • UC San Diego Moores Cancer Center

    La Jolla, California, 92093, United States

  • West China School of Medicine/West China Hospital of Sichuan University

    Chengdu, Sichuan, China

  • Yantai Yuhuangding Hospital (Department of Medical Oncology, 1)

    Yantai, China

  • Zhejiang University Cancer Hospital

    Hangzhou, Zhejiang, China

  • Zhongshan Hospital of Fudan University (Hepatological Surgery Department)

    Shanghai, China

  • Zhongshan Hospital of Fudan University (Medical Oncology Department)

    Shanghai, China