Pulpitis

This study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…

This study tests whether using personalized dosing (based on drug levels in the blood) for the antibiotic teicoplanin works better than standard dosing for treating bacterial infections. About 74 adults in hospital intensive care or other units will take part. The goal is to see …

This study compares three modern dental materials used to treat deep cavities in children's permanent molars by preserving the tooth nerve. The goal is to see which material best helps the tooth root continue growing and reduces pain. About 48 healthy children aged 7 to 11 with o…

This study compares three dental procedures—pulpotomy, partial pulpotomy, and direct pulp capping—all using a material called MTA, to treat deep cavities in children's baby molars. The goal is to see which technique best preserves the tooth, prevents pain, and avoids infection. T…

This study compares two treatments for infected baby molars in children aged 3 to 8: a less invasive method using a triple antibiotic paste versus a standard root canal with a calcium hydroxide-iodoform paste. The goal is to see which approach better relieves pain, swelling, and …

This study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…

This study looks at whether a special light-activated dye can kill more bacteria and reduce pain after root canal treatment. Fifty adults with infected teeth will receive either standard care or the light therapy. The goal is to see if this simple addition improves healing and co…

This study tests two calcium silicate-based dental cements, Biodentine and NeoPutty, for treating irreversible pulpitis (severe tooth nerve inflammation) in adults. Sixty participants with deep cavities and spontaneous pain will receive a single-session pulpotomy, where the infla…

This study tests whether using cold or laser-activated fluids during a root canal can reduce pain and kill more bacteria than standard treatment. Sixty adults with an infected lower molar will receive one of four rinses: room-temperature, cold, heated, or laser-activated sodium h…

This study tests whether taking vitamin D3 before a root canal can reduce pain afterward. Fifty-four adults with low vitamin D and painful tooth inflammation will receive either a single high dose, a three-day course, or a placebo. Pain levels and painkiller use will be tracked f…

This study compares two treatments for severe tooth pain: vital pulp therapy, which tries to save the tooth's nerve, and standard root canal treatment, which removes it. Researchers will measure pain after 24 hours and one week, and check healing at 6 and 12 months using AI to re…

This study looks at whether rinsing with a green tea extract (EGCG) during a tooth-saving procedure (pulpotomy) can lower pain and improve success rates in adults with severe tooth decay. 64 participants with deep cavities will receive one of two rinses and one of two filling mat…

This study tests two ways to clean a tooth during a root canal: laser-activated irrigation and passive ultrasonic irrigation. Researchers want to see which method leads to less pain and better quality of life afterward. 90 adults with infected or damaged permanent teeth are takin…

This study looks at pain after root canal treatment in adults with a tooth condition called irreversible pulpitis. Researchers are testing three different sealers (materials used to fill the root canal) to see which one leads to the least pain and need for painkillers. 75 partici…

This study looks at whether applying cold therapy (cryotherapy) during a pulpotomy—a procedure to save a decayed tooth—can lower pain and improve quality of life afterward. About 82 adults with severe tooth pain will be treated, and their pain levels and daily comfort will be tra…

This study looks at different ways to clean a tooth during a root canal to see which causes the least pain and improves quality of life. 90 adults with a specific type of tooth infection will be randomly assigned to one of three irrigation methods. They will report their pain lev…

This study tests whether a single injection of dexamethasone (a steroid) near the tooth can reduce pain after root canal treatment for people with severe, irreversible tooth inflammation. 44 adults with this condition will receive either the steroid or a placebo (salt water) inje…

This study looks at whether using cold, hot, or ultrasound-activated rinsing solutions can lower pain and bacteria after a root canal. Sixty adults with painful tooth pulp inflammation will receive one of four rinsing methods. The goal is to find which approach works best for a m…

This study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…

This study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…

This study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…

This study looks at how the size of root canal preparation and the amount of remaining tooth structure affect the survival of treated lower molars. Sixty patients with infected pulp will receive either a conventional or conservative root canal preparation. Researchers will track …

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study compares two methods for measuring root canal length during root canal treatment: a manual technique using hand instruments and a machine-assisted mechanical technique. Both methods use electronic devices called apex locators to improve accuracy. About 104 adults needi…

This study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study measures how hot the inside of a tooth gets when dentists shave off a tiny bit of enamel (a common step before braces). Researchers will test two different tools on 40 teeth from 30 people to see which method causes less heat. Keeping the tooth cool is important becaus…

This study looks at whether a person's genetic makeup influences how well a dental treatment called vital pulp therapy works for saving teeth with pulpitis (tooth nerve inflammation). Researchers will collect saliva from 96 participants to analyze specific genes, then track treat…

This study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…

This study looks at whether certain inflammation markers in the blood can predict how well dental numbing shots work and how much pain people feel after treatment. Researchers will analyze blood samples from 150 adults with tooth inflammation (irreversible pulpitis) and compare t…